Complete Uterine Septum with Duplicate Cervix, Longitudinal Vaginal Septum and Unilateral Vaginal Obstruction (Herlyn-Werner-Wunderlich Syndrome): A Case Report of a Mullerian Duct Anomaly

In: Women’s Health Bulletin, Vol 8, Iss 2, Pp 122-125 (2021) · 2021 · doi:10.30476/whb.2021.89645.1101 · W3167708218
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This case report describes Herlyn-Werner-Wunderlich Syndrome, a rare Mullerian duct anomaly with a complete uterine septum and duplicate cervix, treated surgically for pelvic pain.

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AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text

This case report describes a woman with Herlyn-Werner-Wunderlich syndrome, a rare Müllerian duct anomaly, characterized by complete uterine septum with duplicate cervix, a longitudinal vaginal septum, and unilateral vaginal obstruction, presenting with pelvic pain. The authors report management through surgical treatment performed at Imam Reza Hospital in April 2018, aiming to address the syndrome as well as the pelvic pain. They note that HWWs is not included in the American Fertility Association’s current classification system of Müllerian abnormalities and is based on a typical caudal-to-cranial pattern of development; a limitation is that the paper is a single case with no comparative data. Relevance to endometriosis: the paper highlights Herlyn-Werner-Wunderlich syndrome as being associated with endometriosis among other gynecologic complications, though the case report itself is not a study of endometriosis specifically.

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Abstract

Introduction:Herlyn-Werner-Wunderlich Syndrome (HWWs) is a rare variant of Mullerian duct anomalies. It is associated with a wide range of gynecological and obstetric complications, such as urinary incontinence, urinary retention, endometriosis, pelvic infection, pelvic pain and infertility. Case presentation: We conducted the present study to investigate and manage HWWs with pelvic pain. The surgery was performed on the operative room of Imam Reza Hospital in April 2018. Conclusion: The reported case is related to Herlyn-Werner-Wunderlich Syndrome, a rare congenital Mullerian duct anomaly, which it is not included in the current classification system of the Mullerian abnormalities of the American Fertility Association and is based on the typical pattern of caudal evolution towards cranial.
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Women’s Health Bulletin (Apr 2021) Complete Uterine Septum with Duplicate Cervix, Longitudinal Vaginal Septum and Unilateral Vaginal Obstruction (Herlyn-Werner-Wunderlich Syndrome): A Case Report of a Mullerian Duct Anomaly Abstract Introduction:Herlyn-Werner-Wunderlich Syndrome (HWWs) is a rare variant of Mullerian duct anomalies. It is associated with a wide range of gynecological and obstetric complications, such as urinary incontinence, urinary retention, endometriosis, pelvic infection, pelvic pain and infertility. Case presentation: We conducted the present study to investigate and manage HWWs with pelvic pain. The surgery was performed on the operative room of Imam Reza Hospital in April 2018. Conclusion: The reported case is related to Herlyn-Werner-Wunderlich Syndrome, a rare congenital Mullerian duct anomaly, which it is not included in the current classification system of the Mullerian abnormalities of the American Fertility Association and is based on the typical pattern of caudal evolution towards cranial. Keywords

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