EXPERIMENTAL STUDY OF THE RAT EMT MODEL TREATED WITH TRADITIONAL CHINESE MEDICINE XIAO ZHENG TANG

Objective To study the therapeutic effects of traditional Chinese medicine(Xiao Zheng Tang) on endometriosis(EMT) model rats. Methods Firstly, to reproduce rat endometriosis model, secondly, three weeks after operation, EMT model rats were randomly divided into 4 groups:3 experimental groups and 1 control group. Experimental groups were poured Chinese medicine down the throat with Xiao Zheng Tang 0.5ml,1.0ml,1.5ml respectively every day and the control group was treated with 1.0ml H 2O for every rat. Thirdly, to observe the changes of the normal and transplanted endometrium on the 2nd, 4th and 5th week after therapy. Results With the time extending, decreased number of the survived graft, shortened height of epithelium and atrophy of the nucleus of the glandular cells were shown in all experimental groups except for control group. On the 4th week after therapy the graft disappeared in 0.5ml and 1.0ml groups or 1.5ml group on the 2nd week.Conclusion Xiao Zheng Tang inhibits growth of the graft and showed a significant therapeutic effects on EMT model rat.