An Automatic Classification Method of Sleep Apnea Events Based on EEG Frequency Sub-band Division

An Automatic Classification Method of Sleep Apnea Events Based on EEG Frequency Sub-band Division | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article An Automatic Classification Method of Sleep Apnea Events Based on EEG Frequency Sub-band Division Yao Wang, Xiaohong Wang, Weiming Li, Siyu Ji, Tianshun Yang, Xiao Zhuangwen, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-727813/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Sleep apnea is a kind of sleep disorder with a high prevalence rate. It is manifested as the abnormal stop of breathing during sleep and is highly dangerous to human health. The purpose of this research is to find a simple, and effective feature extraction method that can able to distinguish obstructive apnea events, central apnea events, and normal breathing events. Unlike conventional methods, the method illustrated in this study used the Infinite Impulse Response Butterworth Band pass filter to divide the Electroencephalogram (EEG) signal into 5, 7, 9 or 11 frequency sub-bands and then used the Welch method to extract the power features of these frequency sub-band signals, which were subsequently used as classifier input. Random forest, K-nearest neighbors and bagging classifiers were investigated. The results showed that in several different frequency sub-band division methods of EEG signals, the features extracted from the EEG signal that was divided into 11 frequency sub-bands were more conducive to the classification of sleep apnea events. The random forest classifier achieved the highest average accuracy, macro F1 and kappa coefficient in three types of events, which were 90.43%, 90.38% and 0.88, respectively. Compared with existing methods, the method used in the present study has higher classification performance. Computational Biology Bioinformatics Artificial Intelligence and Machine Learning Sleep apnea EEG signal Frequency division Welch method Random Forest Machine learning algorithms. Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-727813","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":40372753,"identity":"f3be7b16-9c2a-4eff-8510-e60746c5ef8c","order_by":0,"name":"Yao Wang","email":"","orcid":"","institution":"Tiangong University","correspondingAuthor":false,"prefix":"","firstName":"Yao","middleName":"","lastName":"Wang","suffix":""},{"id":40372754,"identity":"0792ed0e-07bd-47a8-9a8a-13d3eb8210a5","order_by":1,"name":"Xiaohong Wang","email":"","orcid":"","institution":"Tiangong 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It is manifested as the abnormal stop of breathing during sleep and is highly dangerous to human health. The purpose of this research is to find a simple, and effective feature extraction method that can able to distinguish obstructive apnea events, central apnea events, and normal breathing events. Unlike conventional methods, the method illustrated in this study used the Infinite Impulse Response Butterworth Band pass filter to divide the Electroencephalogram (EEG) signal into 5, 7, 9 or 11 frequency sub-bands and then used the Welch method to extract the power features of these frequency sub-band signals, which were subsequently used as classifier input. Random forest, K-nearest neighbors and bagging classifiers were investigated.\u003c/p\u003e \u003cp\u003eThe results showed that in several different frequency sub-band division methods of EEG signals, the features extracted from the EEG signal that was divided into 11 frequency sub-bands were more conducive to the classification of sleep apnea events. The random forest classifier achieved the highest average accuracy, macro F1 and kappa coefficient in three types of events, which were 90.43%, 90.38% and 0.88, respectively. 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