Uterine Artery Embolization Treatment for Adenomyosis

In: Adenomyosis · 2021 · pp. 113–121 · doi:10.1007/978-981-33-4095-4_12 · W3129688950
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Uterine artery embolization (UAE) is presented as an effective uterine-preserving alternative for symptomatic adenomyosis patients unwilling or unable to undergo surgical treatments.

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This paper describes uterine artery embolization (UAE) as a treatment option for symptomatic adenomyosis, particularly for patients who want to preserve the uterus or avoid surgery due to fear, contraindications, or other reasons. It compares UAE with surgical approaches (including difficulty of adenomyosis excision for diffuse disease) and conservative hormonal/medical therapies, highlighting limitations such as poor compliance with long-term oral contraceptives, irregular bleeding with LNG-IUS, and menopausal symptoms from GnRH-a. The paper states that UAE has nearly a 20-year history and has achieved satisfactory clinical efficacy, with advantages including uterus preservation, easier operation, quick recovery, and few postoperative complications, though it does not provide detailed patient-level methods or outcomes in the provided text. Relevance to endometriosis: the chapter cites research on the relationship between MRI features of adenomyosis and endometriosis phenotypes (Chapron et al., 2017), though its main focus is UAE treatment for adenomyosis.

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Abstract

For symptomatic patients with adenomyosis, a variety of treatment options are available based on the patient’s age, physical and psychological needs, and traditional treatment methods. These treatments include surgical removal, subtotal hysterectomy, or total hysterectomy. However, the surgical removal of adenomyosis is difficult and not satisfactory for diffuse adenomyosis; thus, it is not often performed. Adenomyosis also increasingly begins at a younger age of onset, and there is a need to retain the uterus. In addition to the above surgical treatment, oral contraceptives, Mirena (LNG-IUS), gonadotropin-releasing hormone agonist (GnRH-a), and other conservative treatments are also options for managing adenomyosis. The poor compliance of long-term oral contraceptives, the irregular vaginal bleeding after LNG-IUS, and menopausal symptoms of the expensive GnRH-a contribute to the short-term use of these methods. Therefore, for patients who require treatment for their symptoms, but unwilling to undergo surgical treatment because they are afraid of surgery or have other reasons not to undergo surgery (such as medical and surgical contraindications or religious beliefs), there is a choice of uterine artery embolization (UAE) method. This interventional embolization technology has a history of nearly 20 years and has achieved satisfactory clinical efficacy [1]. Its advantages are the preservation of the uterus, easy operation, quick recovery after surgery, and few postoperative complications. Therefore it has become one of the effective alternatives in the treatment of symptomatic adenomyosis. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

de Bruijn AM, et al. Uterine artery embolization for the treatment of adenomyosis: a systematic review and meta-analysis. J Vasc Interv Radiol. 2017;28(12):1629–1642. e1. Keung JJ, Spies JB, Caridi TM. Uterine artery embolization: a review of current concepts. Best Pract Res Clin Obstet Gynaecol. 2018;46:66–73. Von Korff M, et al. Grading the severity of chronic pain. Pain. 1992;50(2):133–49. Deshmukh SP, et al. Role of MR imaging of uterine leiomyomas before and after embolization. Radiographics. 2012;32(6):E251–81. Chapron C, et al. Relationship between the magnetic resonance imaging appearance of adenomyosis and endometriosis phenotypes. Hum Reprod. 2017;32(7):1393–401. Liu Ruilei DE, Chunlin C, Ping L. The construction of digital three-dimensional model of the pelvic and abdominal pelvic artery vascular network and its application in the uterine arterial embolism entrance planning. Chinese Journal of Obstetrics and Gynecology. 2014;002:89–93. Chen Chunlin CL, Lei T, Ping L, Jianxuan L, Bin C, Hui D, Jun W. The digital three-dimensional model of the abdominal pelvic vascular guides the selection of intravascular intervention intubation. Chinese Journal of cardiovascular diseases. 2015;24(3):252–6. Jiang Bingyang LP. The choice of 3D reconstruction technology and individual treatment options for uterine adenomyosis. Chinese Journal of Practical Gynaecology and Obstetrics. 2017;33(2):141–5. Worthington-Kirsch R, et al. The Fibroid registry for outcomes data (FIBROID) for uterine embolization: short-term outcomes. Obstet Gynecol. 2005;106(1):52–9. Author information Authors and Affiliations Editor information Editors and Affiliations Rights and permissions Copyright information © 2021 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. About this chapter Cite this chapter Fan, Z. (2021). Uterine Artery Embolization Treatment for Adenomyosis. In: Xue, M., Leng, J., Wong, F. (eds) Adenomyosis. Springer, Singapore. https://doi.org/10.1007/978-981-33-4095-4_12 Download citation DOI: https://doi.org/10.1007/978-981-33-4095-4_12 Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-33-4094-7 Online ISBN: 978-981-33-4095-4 eBook Packages: MedicineMedicine (R0)

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