The clinical efficacy of levonorgestrel intrauterine device on endometriosis patients after surgery

Objective To observe the clinical efficacy of levonorgestrel intrauterine device (IUD) on endometriosis patients after surgery.Methods Eighty-four endometriosis patients diagnosed by pathological and surgery were divided into control group and treatment group by random digits table with 42 cases each group.The control group was accepted only short-term drug treatment,while the treatment group was placed levonorgestrel intrauterine device on the basis of control group,then comparing the efficacy after followed up for one year.Results The mean pain score of treatment group was 0,control group was (1.5 ±0.2) points,the difference was statistically significant (P＜ 0.05).The menstrual blood volume and CA125 levels in treatment group were significantly lower than those in control group [(11 ± 3)％ vs.(45 ± 6)％,(7.01 ±2.97) U/L vs.(38.79 ±31.43) U/L] (P ＜0.05).The recurrence rate in treatment group was significantly lower than that in control group [2.38％ (1/42) vs.28.57％ (12/42),P ＜ 0.05].Conclusion Endometriosis set levonorgestrel IUD after therapy can relieve postoperative pain and reduce menstrual flow,reduce lesion recurrence rate,its clinical effect is significant. Key words: Endometriosis;  Levonorgestrel;  Pain;  Contraception