Genetic and Embryological Basis with Clinical Implications of Lobulated Kidney: A Cadaveric Study

Introduction: Lobation of kidney is a normal stage during development. Persistent foetal lobulations of kidneys may mimick inflammatory conditions like renal scars in CT and also mistaken for a tumour. It may lead to errors in diagnosis and resulting in unwanted investigations and interventions. The present study’s main emphasis was to look for foetal lobulations in adult kidneys, study its genetic and embryological basis as well as describe its clinical significance. Materials: and methods This observational study includes 25 formalin-fixed cadavers, sourced from Subbaiah Institute of Medical Sciences, Shimoga, Karnataka, India, during the period of 2015–21. Total of 50 kidneys were observed for lobulations and data obtained was tabulated. Results: Of the 25 right and 25 left kidneys, five kidneys showed lobulations, among which 2 were right and 3 left. Conclusion: In the present study, we found 8% of lobulations on right side and 12% on left side. The knowledge of lobulations is of importance in distinguishing a pathological kidney from a normal sized healthy kidney