Diagnosis and Treatment of Interstitial Cystitis/Painful Bladder Syndrome: A Review

Butrick CW, Charles W. Butrick, Fred M. Howard, Howard FM, Peter K. Sand, Sand Pk
Journal of women's health (2002) · 2010 · vol. 19(6) , pp. 1185–1193 · doi:10.1089/jwh.2009.1702 · PMID:20491565 · W2155116246
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This review discusses interstitial cystitis/painful bladder syndrome, a chronic disorder of pelvic pain and urinary urgency, and outlines its differential diagnosis, likely multifactorial etiology, and multimodal treatment approaches.

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Abstract

Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic bladder disorder characterized by pelvic pain and irritative voiding symptoms. The symptoms of IC/PBS can overlap with such conditions as endometriosis, recurrent urinary tract infection, chronic pelvic pain, overactive bladder, and vulvodynia. The etiology of IC/PBS is likely multifactorial and may involve a defective urothelium, neurogenic upregulation, and mast cell activation. A thorough patient history and physical examination are critical in the differential diagnosis of IC/PBS. Frequent follow-up and patient education are important components of treatment once a condition is diagnosed. A multimodal approach to therapy can provide optimal relief for patients with IC/PBS.

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Condition tags

endometriosischronic_pelvic_paininterstitial_cystitis

MeSH descriptors

Cystitis, Interstitial Combined Modality Therapy Cystitis, Interstitial Cystitis, Interstitial Diagnosis, Differential Humans

Citation neighborhood

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References (81)

Cited by (2)

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