5-Aminolevulinic acid photodynamic therapy and isotretinoin for treatment of drug-induced acne fulminans in a patient with idiopathic thrombocytopenic purpura
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This paper reports the successful treatment of drug-induced acne fulminans in a patient with idiopathic thrombocytopenic purpura using 5-aminolevulinic acid photodynamic therapy combined with isotretinoin.
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Abstract
In this work, we present a case of deteriorative acne that occurred during methylprednisolone and danazol treatment of idiopathic thrombocytopenic purpura (ITP). Treatment of the patient with a combination of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) and isotretinoin was satisfactory, though the patient had platelets as low as 4-10 × 109/L during treatment. We consider that the combination of oral isotretinoin and ALA-PDT was effective in this patient may be due to the synergetic effect of these treatments. To the best of our knowledge, no such cases have been reported.
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References (6)
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SciLite annotations
chemicals 7
5-aminolevulinic acid
isotretinoin
prednisolone
danazol
5-aminolevulinic acid
isotretinoin
isotretinoin
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- last seen: 2026-05-11T06:27:45.971503+00:00
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- last seen: 2026-05-18T04:26:01.642840+00:00
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