1H-Pyrazoles Useful In Therapy

Compounds of formula (I), or a pharmaceutically acceptable derivative thereof, wherein Rand Rindependently represent H, C1-6alkyl, C3-8cycloalkyl, or halogen; Rrepresents C1-6alkyl, CF3 or aryl; a represents 1 or 2; R, R, Rand Rindependently represent H, C1-6alkyl, C1-6alkyloxy, CN or halogen, or Rand R, or Rand R, together with the ring to which they are attached form an aryl or heterocyclic fused ring system; X represents C or N; Y represents CH2 or O; Rrepresents H, CN or halo provided that, when X represents N, Ris absent. The compounds are useful for treating endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), or chronic pelvic pain syndrome.