Endometriosis-Associated Malignant Transformation Arising in a Laparotomy Scar: A Case Report and Literature Review

Keti Kebadze, Tsotne Dadiani, Niko Koridze
In: Science, Education and Innovations in the context of modern problems · 2025 · vol. 8(9) , pp. 220–227 · doi:10.56334/sei/8.9.22 · W4412500897
article OA: bronze CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-14 ⓘ

This report describes a rare case of malignant transformation of endometriosis within a laparotomy scar, discussing the histopathological diagnosis and reviewing fewer than 50 prior cases of this phenomenon.

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Abstract

Background:Endometriosis is a common estrogen-dependent condition, affecting approximately 10% of women of reproductive age.It is characterized by the presence of endometrial-like tissue outside the uterine cavity.While malignant transformation of endometriosis typically occurs in ovarian tissue, such transformation at extraovarian sitesparticularly within abdominal wall scars-is exceedingly rare. Case Summary:Fewer than 50 cases of malignancies arising from abdominal wall scar endometriosis have been reported globally.The most commonly observed histological types include clear cell carcinoma and endometrioid adenocarcinoma.Diagnosis requires comprehensive histopathological and immunohistochemical analysis.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK