OP30.03: Evaluation of effects of ultrasound‐guided radiofrequency ablation on adenomyosis by using contrast enhanced ultrasonography

To evaluate the effects of ultrasound-guided radiofrequency ablation (RFA) on adenomyosis by using contrast enhanced ultrasonography (CEUS). Adenomyosis is one of the most common benign disorders which affects 10-15% of all women in reproductive age. Ultrasound-guided radiofrequency ablation (RFA) has been applied to coagulate the local tissues, which is accepted as one technique showing excellent local control and acceptable morbidity. In the current study, we employed CEUS for evaluation of therapeutic effects of ultrasound-guided RFA on 125 patients with adenomyosis in our hospital, in order to assess the role of CEUS for post-ablation observation. 125 patients with adenomyosis were ablated via ultrasound-guided RFA. CEUS was performed before ablation and 1, 3, 6 12 months after ablation. Characteristics of vascular perfusion of lesions was assessed as follows: homogeneous, heterogeneous, no perfusion, surrounding vessels on CEUS before and after ablation. Serum antigen CA125 and hemoglobin was observed. And pathological results was acquired via biopsy. The size of adenomyosis lesions was 2.7 ± 1.1 cm. Before ablation, 72% lesions presented homogeneous enhancement, while the others were detected as heterogeneous enhancement. One month after ablation, 85% lesions showed no perfusion which indicated the total necrosis of the lesions. The necrosis of ablated areas was identified in pathological results. 15% lesions presented surrounding vessels but no central perfusion. Three months after ablation, 5% lesions had lower enhancement than the surrounding tissues, which may indicated the residuals. Six months after ablation, clinical symptoms of all the patients were improved and uterine volume were decreased. The level of CA125 was decreased month by month. Hemoglobin achieved normal gradually. CEUS has an important role in evaluation of the foci and the therapeutic effects on adenomyosis.