Mullerianosis of the Urinary Bladder: A Rare Case Report

Mullerianosis of the Urinary Bladder: A Rare Case Report DOI: https://doi.org/10.21276/apalm.3688Keywords: müllerianosis, endocervicosis, endometriosis, endosalpingosis, case reportAbstract Endocervicosis, endometriosis, and endosalpingosis are choristomas derived from Müllerian tissue, collectively termed Müllerianosis. We report a 40-year-old woman with pelvic pain and dysuria who presented with a 3.2×2.5 cm bladder mass four years post-hysterectomy. Transurethral resection revealed endocervical glands and endometrial stroma deep in the bladder wall. Immunohistochemistry confirmed ER/PR positivity in glandular epithelium and CD10 positivity in stroma, establishing the diagnosis of Müllerianosis. Outcome: The patient remained asymptomatic with no recurrence over 8 years of clinical and cystoscopic follow-up. Müllerianosis is a rare benign bladder lesion that can mimic malignancy. Accurate histopathological diagnosis with immunohistochemistry is essential to avoid unnecessary radical surgery and enable hormonal therapy when indicated.References 1. Young RH, Clement PB. Müllerianosis of the urinary bladder. Mod Pathol. 1996;9(7):731-7. 2. Donné C, Vidal M, Buttin X, et al. Müllerianosis of the urinary bladder: clinical and immunohistochemical findings. Histopathology. 1998;33(3):290-2. 3. Koren J, Mensikova J, Mukensnabl P. Müllerianosis of the urinary bladder: report of a case with suggested metaplastic origin. Virchows Arch. 2006;449:268-71. 4. Branca G, Barresi V. Müllerianosis of the urinary bladder: a rare tumorlike lesion. Arch Pathol Lab Med. 2014;138(3):432-6. 5. Vella JE, Nair N, Ferryman SR. Müllerianosis of the urinary bladder. Int J Surg Pathol. 2011;19(4):548-51. 6. Guan H, Rosenthal DL, Erozan YS. Müllerianosis of the urinary bladder: report of a case with diagnosis suggested in urine cytology and review of literature. Diagn Cytopathol. 2012;40(11):997-1001. 7. Ogah K, Hartis R, Hilton P. Müllerianosis involving the urinary bladder. Int Urogynecol J. 2012;23(Suppl 2):S123-5. 8. Mardi K, Verma S. Müllerianosis of the urinary bladder: a great mimicker. Arch Urol Res. 2024;8(1):005-007. 9. Wegrzyn GH, Kilianek M, Iwaz S. Müllerianosis of the urinary bladder: a case report. Can J Urol. 2024;31(1):11809-12. Downloads Published Issue Section License Copyright (c) 2026 Richa Bhartiya, Pallavi Mehra, Vishal Tayade, Navin Kumar Bariar This work is licensed under a Creative Commons Attribution 4.0 International License. Authors who publish with this journal agree to the following terms: - Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. - Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. - Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access at http://opcit.eprints.org/oacitation-biblio.html).