Gonodotropine releasing hormone agonist plus laparoscopic surgery in the treatment of endometriosis and infertility

Objective To study the efficacy of Gonodotropine releasing hormone agonist plus laparoscopic surgery in endometriosis associated with infertility and the analysis in different subgroups of endometriosis.Methods One hundred and six cases with endometriosis and infertility who accepted laparoscopic surgery(LS)were divide into mild and severe groups according to r-AFS criteria for EMS,and followed up for 1 year.Moreover,two groups were divided into therapeutic subgroup(LS plus GnRH-a)and control subgroup(LS).Data of remission,recurrence and pregnancy after treatment were collected and analyzed.Results There was no significant difference in the ratios of remission,recurrence and pregnancy between control and therapy subgroups in mild EMS group.The same results of remission happened to severe EMS group,however,a low ratio of recurrence and a high ratio of pregnancy were revealed.Conclusions It is necessary for patients with severe EMS group after LS to add endocrinal therapy.The effect of LS plus GnRH-a is prior to LS.LS plus GnRH-a may increase the pregnancy rate and decrease the recurrence rate in severe EMS.