sQUIZ your knowledge! A tender nodule in the umbilicus of a young fertile woman.
A 41-year-old woman presented with a tender, cyclically enlarging umbilical nodule that histopathological analysis identified as endometriosis.
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This case report describes a 41-year-old woman presenting with a progressively enlarging, tender umbilical nodule that exhibited cyclic pain and swelling coinciding with her menstrual cycle. Physical examination identified a blue-brownish subcutaneous lesion, and subsequent histopathological analysis confirmed the presence of glandular tissue consistent with ectopic endometrial implants. The clinical presentation and pathological findings support a diagnosis of umbilical endometriosis, also known as endometrioma of the umbilicus or Sister Mary Joseph nodule in this specific context. This paper is centrally about endometriosis — specifically cutaneous endometriosis manifesting as an umbilical nodule.
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- europepmc
- last seen: 2026-09-20T09:27:46.357103+00:00
- unpaywall
- last seen: 2026-09-24T06:17:16.569905+00:00