Short-term Efficacy Comparison of Intracorporeal versus Extracorporeal Ileocolonic Anastomosis in Right Hemicolectomy for Colon Cancer---A Single-Center, Retrospective Study

Short-term Efficacy Comparison of Intracorporeal versus Extracorporeal Ileocolonic Anastomosis in Right Hemicolectomy for Colon Cancer---A Single-Center, Retrospective Study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Short-term Efficacy Comparison of Intracorporeal versus Extracorporeal Ileocolonic Anastomosis in Right Hemicolectomy for Colon Cancer---A Single-Center, Retrospective Study Jun Zhang, Xirang Wang, Yunpeng Wu, Yuxiang Li This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8625582/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background Intracorporeal versus extracorporeal ileocolonic anastomosis are two anastomotic approaches in laparoscopic right hemicolectomy for colon cancer. The comparative advantages of these two techniques remain clinically debated. Therefore, this study was conducted to provide reference for clinical decision-making. Aim To investigate the short-term efficacy of intracorporeal ileocolic anastomosis (IIA) in right hemicolectomy for colon cancer. Methods Clinical data of patients who underwent laparoscopic right hemicolectomy in the Department of General Surgery, Beijing Fengtai You'anmen Hospital between December 2021 and November 2025 were retrospectively collected and analyzed. Patients were divided into two groups based on the ileocolonic anastomosis technique: the observation group (IIA group), where the anastomosis was performed intracorporeally, and the control group (extracorporeal ileocolic anastomosis [EIA] group), where the anastomosis was performed extracorporeally. Relevant clinical indicators were compared between the two groups. Results A total of 132 patients were included in this study, with 62 in the observation group and 70 in the control group. Baseline characteristics were comparable between the two groups, with no statistically significant differences (P > 0.05). There were no perioperative mortalities in either group. The observation group demonstrated superior outcomes in terms of total abdominal incision length, time to first flatus postoperatively, and incision pain scores on postoperative days 1 and 3 compared to the control group, with statistically significant differences (P < 0.05). The duration of the ileocolonic anastomosis was longer in the observation group, showing a statistically significant difference (P < 0.05). There were no statistically significant differences between the two groups regarding total operative time, intraoperative blood loss, number of lymph nodes harvested, postoperative hospital stay, white blood cell levels and albumin levels on postoperative days 1, 3, and 5, abdominal drainage volume, incision pain score on postoperative day 5, or the incidence of postoperative complications (P > 0.05). Conclusion Intracorporeal anastomosis in right hemicolectomy for colon cancer can facilitate faster recovery of bowel function, shorten abdominal incisions, and reduce early postoperative incision pain, without increasing the complication rate. It is clinically proven to be safe and effective, demonstrating good application value. Intracorporeal Ileocolic Anastomosis Extracorporeal Ileocolic Anastomosis Right Colon Cancer Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-8625582","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":578652435,"identity":"d05c087a-65aa-4c7d-97b9-4d6fc8a23eca","order_by":0,"name":"Jun Zhang","email":"","orcid":"","institution":"Beijing Fengtai You'anmen Hospital","correspondingAuthor":false,"prefix":"","firstName":"Jun","middleName":"","lastName":"Zhang","suffix":""},{"id":578652436,"identity":"c6607eee-8ede-44b3-8ccf-c1dd17fa936d","order_by":1,"name":"Xirang Wang","email":"","orcid":"","institution":"Beijing Fengtai You'anmen Hospital","correspondingAuthor":false,"prefix":"","firstName":"Xirang","middleName":"","lastName":"Wang","suffix":""},{"id":578652437,"identity":"998a33de-bcf2-4bd0-a04d-ec77ffcc0d81","order_by":2,"name":"Yunpeng Wu","email":"","orcid":"","institution":"Beijing Fengtai You'anmen Hospital","correspondingAuthor":false,"prefix":"","firstName":"Yunpeng","middleName":"","lastName":"Wu","suffix":""},{"id":578652438,"identity":"7116dba1-75f4-4efb-8908-ec259a9aa6b7","order_by":3,"name":"Yuxiang Li","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA4ElEQVRIie3QIQ7CMBSA4S5NOtMwW5JlCC4wzBSHaUMyVRLkBAlLRpiAgZ3jCuCQXUiqOjRyHAGHAoqG0OEQ/XT/vPcKgGX9IeRmQlCMZltvc2loMjUnHSyZaPyOsy8VDBslzUlAeL9qhoGTCo66lzlssRhWQFAeQSetZcJSBLx8SQ23FPoWFSMXruMzO/iAqHpnmHKigq0k1ptFZ6YQCMnYkBAeCnZ/EL1eNGEL2DLRnxwCwSPQLsGSvhI6KOWIUCWx8ZZenh2vN530vKy63pJp4OXF9+QN/u25ZVmW9dETU+5QAW0/I2cAAAAASUVORK5CYII=","orcid":"","institution":"Beijing Fengtai You'anmen Hospital","correspondingAuthor":true,"prefix":"","firstName":"Yuxiang","middleName":"","lastName":"Li","suffix":""}],"badges":[],"createdAt":"2026-01-17 11:23:22","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-8625582/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-8625582/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":105564295,"identity":"25890613-1cd3-479a-bd83-e6b54d8e695e","added_by":"auto","created_at":"2026-03-27 12:49:12","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":343436,"visible":true,"origin":"","legend":"","description":"","filename":"ShorttermEfficacyComparisonofIntracorporealversusExtracorporealIleocolonicAnastomosisinRightHemicolectomyforColonCancerASingleCenterRetrospectiveStudy.pdf","url":"https://assets-eu.researchsquare.com/files/rs-8625582/v1_covered_13da02fa-f6cc-44f7-be37-8fcdca7150b1.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Short-term Efficacy Comparison of Intracorporeal versus Extracorporeal Ileocolonic Anastomosis in Right Hemicolectomy for Colon Cancer---A Single-Center, Retrospective Study","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Intracorporeal Ileocolic Anastomosis, Extracorporeal Ileocolic Anastomosis, Right Colon Cancer","lastPublishedDoi":"10.21203/rs.3.rs-8625582/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-8625582/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eIntracorporeal versus extracorporeal ileocolonic anastomosis are two anastomotic approaches in laparoscopic right hemicolectomy for colon cancer. The comparative advantages of these two techniques remain clinically debated. Therefore, this study was conducted to provide reference for clinical decision-making.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAim\u003c/strong\u003e To investigate the short-term efficacy of intracorporeal ileocolic anastomosis (IIA) in right hemicolectomy for colon cancer.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods\u003c/strong\u003e Clinical data of patients who underwent laparoscopic right hemicolectomy in the Department of General Surgery, Beijing Fengtai You'anmen Hospital between December 2021 and November 2025 were retrospectively collected and analyzed. Patients were divided into two groups based on the ileocolonic anastomosis technique: the observation group (IIA group), where the anastomosis was performed intracorporeally, and the control group (extracorporeal ileocolic anastomosis [EIA] group), where the anastomosis was performed extracorporeally. Relevant clinical indicators were compared between the two groups.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e A total of 132 patients were included in this study, with 62 in the observation group and 70 in the control group. Baseline characteristics were comparable between the two groups, with no statistically significant differences (P \u0026gt; 0.05). There were no perioperative mortalities in either group. The observation group demonstrated superior outcomes in terms of total abdominal incision length, time to first flatus postoperatively, and incision pain scores on postoperative days 1 and 3 compared to the control group, with statistically significant differences (P \u0026lt; 0.05). The duration of the ileocolonic anastomosis was longer in the observation group, showing a statistically significant difference (P \u0026lt; 0.05). There were no statistically significant differences between the two groups regarding total operative time, intraoperative blood loss, number of lymph nodes harvested, postoperative hospital stay, white blood cell levels and albumin levels on postoperative days 1, 3, and 5, abdominal drainage volume, incision pain score on postoperative day 5, or the incidence of postoperative complications (P \u0026gt; 0.05).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion\u003c/strong\u003e Intracorporeal anastomosis in right hemicolectomy for colon cancer can facilitate faster recovery of bowel function, shorten abdominal incisions, and reduce early postoperative incision pain, without increasing the complication rate. It is clinically proven to be safe and effective, demonstrating good application value.\u003c/p\u003e","manuscriptTitle":"Short-term Efficacy Comparison of Intracorporeal versus Extracorporeal Ileocolonic Anastomosis in Right Hemicolectomy for Colon Cancer---A Single-Center, Retrospective Study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2026-01-27 17:41:32","doi":"10.21203/rs.3.rs-8625582/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"a514f739-32a8-40c0-8d80-1feb873548a9","owner":[],"postedDate":"January 27th, 2026","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2026-03-23T19:09:30+00:00","versionOfRecord":[],"versionCreatedAt":"2026-01-27 17:41:32","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-8625582","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-8625582","identity":"rs-8625582","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}