Usefulness of Oxidized Regenerated Cellulose Powder in stopping bleeding during laparoscopic ovarian cystectomy to protect ovarian reserve

Madoka Yamaguchi, Yūko Hasegawa, Ayako Tsumagari, Naoki Kita, Yumi Ochi, Hajime Okamoto
In: JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY · 2022 · vol. 38(2) , pp. 32–36 · doi:10.5180/jsgoe.38.2_32 · W4317924199
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This study investigated oxidized regenerated cellulose powder as a hemostatic agent during laparoscopic ovarian cystectomy to mitigate decreases in ovarian reserve.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 ⓘ

The paper studied whether oxidized regenerated cellulose powder used for hemostasis during laparoscopic ovarian cystectomy can protect ovarian reserve, with a particular consideration for patients wishing to preserve fertility in cases including endometriotic cysts. Nine patients wishing to have babies underwent cystectomy using oxidized regenerated cellulose powder, and serum anti-Müllerian hormone (AMH) was measured before surgery and again 3 months afterward. The authors reported that the average AMH change was 97.3%, indicating almost no decrease after surgery. This paper is centrally about endometriosis — it explicitly targets ovarian reserve protection in laparoscopic cystectomy in the context of endometriotic cysts by focusing on hemostatic choice and its effect on AMH.

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Abstract

Objective: The treatment strategy for ovarian tumors is often uncertain when a patient wishes to have children. Especially in the case of endometriotic cysts, although pre-assisted reproductive technology ovarian cystectomy does not improve the live birth rate, surgery may be selected considering the symptom and the infertility treatment course. In such cases, it is necessary to pay attention to selecting the hemostatic method for ovarian reserve. It has been reported that hemostasis with suture / hemostatic sealant has a smaller decrease in serum anti-Müllerian hormone (AMH) level than with bipolar coagulation. We focused on this method using a hemostatic sealant.

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infertility

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