ADVANCES IN THE MANAGEMENT OF ENDOMETRIOSIS: CURRENT DIAGNOSTIC AND THERAPEUTIC APPROACHES

Laís Vieira de Lima, Henrique Oliveira Silva, Marcos André Macedo do Vale Silva, Dayvisson Orestes Lopes, Luana Oliveira Rezende, M. Benedetti, Fernanda Montesso Simões De Paiva, Marcella Silva Moraes, Eduarda Luisa Rocha Corti, Maria Eduarda Borges Cartaxo, Isadora Queiroz Martins, Digleane de Fátima Ramos Nascimento
In: International Journal of Health Science · 2023 · vol. 3(96) , pp. 2–8 · doi:10.22533/at.ed.1593962321114 · W4388900877
article OA: bronze CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-22 ⓘ

This review synthesizes current diagnostic methods including clinical evaluation, imaging, CA-125, and laparoscopy, alongside personalized therapeutic options like hormonal drugs, surgery, and assisted reproduction for endometriosis management.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-22 · read from full text ⓘ

This scientific article reviewed the diagnostic methods and therapeutic options for endometriosis, using a comprehensive search of Google Scholar, SciELO, and PubMed covering 2004–2023 in English, Portuguese, and Spanish. It describes a diagnostic approach that combines clinical evaluation, imaging (transvaginal ultrasound and magnetic resonance imaging), and serum CA-125 testing, noting that laparoscopy is typically required for definitive diagnosis despite being invasive. It concludes that endometriosis treatment should be individualized to address pelvic pain and/or infertility, with options including hormonal drug therapy, surgery (with preference for conservative organ-conserving procedures because symptom severity does not directly correlate with disease extent), and assisted reproduction; it also states ovarian suppression alone is not recommended to improve fertility except as preparation for IVF. This paper is centrally about endometriosis—providing a comprehensive overview of current diagnostic and therapeutic approaches for endometriosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

This scientific article offers a comprehensive overview of endometriosis, covering diagnostic methods and available therapeutic options. The research methodology included a comprehensive search in three academic databases (Google Scholar, Scielo and PubMed) from 2004 to 2023, encompassing articles in English, Portuguese and Spanish. The search used relevant keywords and established inclusion criteria. The diagnosis of endometriosis involves an approach that takes into consideration, clinical evaluation, imaging tests, such as transvaginal ultrasound and magnetic resonance imaging, and analysis of the serum marker CA-125. Laparoscopy is usually necessary for a definitive diagnosis, although it is invasive. Endometriosis treatment is highly personalized, focusing on resolving pelvic pain and managing infertility when present. Therapeutic options include drug treatment, surgery and assisted reproduction treatments. The choice of treatment depends on several factors, such as the stage of the disease and other clinical factors. Drug treatment includes different hormonal approaches, but ovarian suppression alone is not recommended to improve fertility except in preparation for IVF. Surgical therapy ranges from less complex procedures to more extensive interventions, focusing on organ conservation. Conservative surgery is preferred as there is no direct correlation between the extent of the disease and the severity of symptoms. Lesion ablation and adhesiolysis can improve fertility, especially in mild to moderate cases. Therefore, it is concluded that the treatment of endometriosis requires a personalized approach, considering the symptoms, stage of the disease and the patient's reproductive goals, with the aim of providing pain relief and improving quality of life. Diagnosis and treatment must be carefully considered in each case.
Full text 4,419 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Keywords

Endometriosis, pharmacology, diagnosis, therapy -

Abstract

This scientific article offers a comprehensive overview of endometriosis, covering diagnostic methods and available therapeutic options. The research methodology included a comprehensive search in three academic databases (Google Scholar, Scielo and PubMed) from 2004 to 2023, encompassing articles in English, Portuguese and Spanish. The search used relevant keywords and established inclusion criteria. The diagnosis of endometriosis involves an approach that takes into consideration, clinical evaluation, imaging tests, such as transvaginal ultrasound and magnetic resonance imaging, and analysis of the serum marker CA-125. Laparoscopy is usually necessary for a definitive diagnosis, although it is invasive. Endometriosis treatment is highly personalized, focusing on resolving pelvic pain and managing infertility when present. Therapeutic options include drug treatment, surgery and assisted reproduction treatments. The choice of treatment depends on several factors, such as the stage of the disease and other clinical factors. Drug treatment includes different hormonal approaches, but ovarian suppression alone is not recommended to improve fertility except in preparation for IVF. Surgical therapy ranges from less complex procedures to more extensive interventions, focusing on organ conservation. Conservative surgery is preferred as there is no direct correlation between the extent of the disease and the severity of symptoms. Lesion ablation and adhesiolysis can improve fertility, especially in mild to moderate cases. Therefore, it is concluded that the treatment of endometriosis requires a personalized approach, considering the symptoms, stage of the disease and the patient's reproductive goals, with the aim of providing pain relief and improving quality of life. Diagnosis and treatment must be carefully considered in each case. - Laís Vieira de Lima - Henrique Oliveira Silva - Marcos André Macedo do Vale Silva - Dayvisson Orestes Lopes - Luana Oliveira Rezende - Maria Fernanda Melo Benedetti - Fernanda Montesso Simões de Paiva - Marcella Silva Moraes - Eduarda Luisa Rocha Corti - Maria Eduarda Borges Cartaxo - Isadora Queiroz Martins - Digleane de Fátima Ramos Nascimento

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosisinfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (7)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK