PATHOGENETIC ASPECTS OF INFERTILITY IN WOMEN OF REPRODUCTIVE AGE WITH OVARIAN VARICOCELE

PATHOGENETIC ASPECTS OF INFERTILITY IN WOMEN OF REPRODUCTIVE AGE WITH OVARIAN VARICOCELE DOI: https://doi.org/10.31435/rsglobal_ws/30062020/7106Keywords: ovarian varicocele, infertility, varicose veins of the pelvis, phlebostasis, ovarian veinAbstract To date, the problem of reduced fertility is quite relevant. At the same time, it should be noted that the effectiveness of infertility treatment, even with the use of the latest techniques, tools and drugs does not exceed 35-40%. This can be explained by insufficient study of a number of causes that lead to impaired fertility. One of these little-known and poorly studied factors is pelvic venous plethora, in particular varicose veins of the ovaries. While anatomically similar disease in men - varicocele - is given great importance, in women, even the very existence of this pathology is controversial among some authors. All studies were conducted in compliance with the basic bioethical norms and requirements of the Declaration of Helsinki. 117 women of reproductive age (21 - 42 years) with infertility of functional genesis were examined. According to the results of the analysis, the clinical and anamnestic features of women with infertility and ovaric varicocele are increased proportion of patients with intellectual differentiation and psycho-emotional and physical stress, high frequency of infectious diseases with acyclic uterine bleeding, dysmenorrhea and premenstrual. Changes in the anatomical and functional state of the pelvic organs and venous system in women with infertility and ovarian varicocele have been established. It was found that the hormonal profile of women with infertility and ovarian varicocele is characterized by a decrease in estradiol and progesterone. A pathogenetically sound algorithm for the diagnosis and treatment of women with infertility and ovarian varicocele has been developed, which is based on clinical data and the results of instrumental methods of examination. References Булавенко, О.В., Григоренко, А.Н., & Сливка, Э.В. (2016). Хирургическая коррекция состояния недостаточности лютеиновой фазы у женщин с варикозным расширением гонадных вен. Сборник трудов конференции, 159-164. Булавенко, О.В. & Дощечкин, В.В. (2017). Ультрасонографическая оценка овуляторной стигмы и проноз исхода роста доминантного фолликула. Репродуктивна ендокринологія, 4 (36), 36-42. Ночвіна,О.А. (2016). Доплерометричні характеристики мозкового кровообігу у жінок із синдромом хронічного тазового болю. Вісник морфології, 1(22), 134-137. Ночвіна, О.А., & Жук, С.І. (2014). Синдром хронічного тазового болю в ґенезі стрес-індукованого безпліддя у жінок репродуктивного віку. З турботою про жінку, 2 (50), 181-184. Чечуга,С.Б. & Силин, Г.А. (2015). Патогенетическое обоснование консервативного лечения овариковарикоцеле у женщин репродуктивного возраста. Репродуктивное здоровье. Восточная Европа, 40 (4), 26-31. Labropoulos, N., Malgor, R.D., Comito, M., Gasparis, A.P. et.al. (2015). The natural history and treatment outcomes of symptomatic ovarian vein thrombosis. J Vasc Surg Venous Lymphat Disord, 3(1), 42-47. Tu, F.F., Hahn, D. & Steege, J.F. (2010). Pelvic congestion syndrome-associated pelvic pain: a systematic review of diagnosis and management. Obstet Gynecol Surv, 65(5), 332-340. Durham, J.D., Machan, L. (2013). Pelvic congestion syndrome. Semin Intervent Radiol, 30(4), 372-380. Hansrani, V., Dhorat, Z. & McCollum, C.N. (2016). Diagnosing of pelvic vein incompetence using minimally invasive ultrasound techniques. Vascular, 25(3), 253-259. Labropoulos, N., Jasinski, P.T., Adrahtas, D. et.al. (2016). Standardized ultrasound approach to pelvic congestion syndrome. Phlebology, 32(9), 608-619. Downloads Published Issue Section License All articles are published in open-access and licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0). Hence, authors retain copyright to the content of the articles. CC BY 4.0 License allows content to be copied, adapted, displayed, distributed, re-published or otherwise re-used for any purpose including for adaptation and commercial use provided the content is attributed.