Therapeutic Regimen Comparison of Artificial Insemination by Donor on Mild Endometriosis

Objective: To investigate the pregnant outcomes of mild endometriosis patients treated by the natural cycle or the induction ovulation cycle pregnancy for artificial insemination by donor( AID) with laparoscopic treatment within 2 years. Methods: 303 cycles( 168 cases) of AID of mild endometriosis patients without ovulation disorders which had the laparoscopic treatment within two years were retrospectively analyzed. The pregnancy rate in the natural cycle group and the induction ovulation cycle group was compared. The pregnancy rate in single follicle ovulation and multi-follicular ovulation cycle in the induction ovulation cycle group was compared. Results: In all patients in the study,47 of the all patients got pregancies,including 33 in the natural cycle group( 16. 9%,33 /195) and 14 in the induction ovulation cycle group( 13. 0%,14 /108). The difference between two groups was not statistically significant( P =0. 362). The pregnancy rate of single follicle ovulation cycle and multi-follicular ovulation cycle( the number of follicles ≤ 3) was 13. 5%( 7 /52) and 12. 5%( 7 /56),respectively in induction ovulation cys. The difference was not statistically significant( P = 0. 882). Conclusions: The natural cycle of artificial insemination should be a better choice to the mild endometriosis patients with normal ovulation.