Lesions of the Lower Uterine Segment: A Review

Background: The lower uterine segment may become involved by cervical as well as endometrial lesions. In addition, there are lesions unique to the lower uterine segment, and identifying carcinomas in this region may have prognostic significance. Objectives: This review covers the scope of lesions affecting the lower uterine segment. Methods: A Medline search was used, using the term lower uterine segment. Reported lesions of the lower uterine segment were reviewed. Results: Endomerial carcinomas arising from, as well as spreading to this area may have prognostic significance. Adenocarcinomas arising in the lower uterine segment can be associated with Lynch syndrome. Endometrial adenocarcinoma spreading to the lower uterine segment may indicate an increased risk of lymph nodal involvement. Conclusions: A review of the scope of lower uterine segment lesions is presented to assist in developing a differential diagnosis if a patient with such a lesion is encountered.