An Evaluation of the Modified Kupperman Index on Climacteric Symptoms in Perimenopausal Women Underwent Bilateral Ovariectomy

Objective:To evaluate the impact of bilateral ovariectomy on climacteric symptoms in perimenopausal women with benign gynecological tumor,as assessed by the modified Kupperman Index.Methods:Perimenopausal women who received bilateral ovariectomy on benign tumor in our department from 2006 to 2007 were recruited.A questionnaire of the modified Kupperman Index(KI) was sent to them postoperative 6 to 12 months.Patients were further asked to decide whether or not,if it were possible,to accept the bilateral ovariectomy.They were grouped as Accept the surgery and Postpone the surgery according to their answers.Pre-and post-operative KI scores were calculated and subjected to statistical analysis.Results:Sixty-eight efficient questionnaires were returned.Mean KI score was increased from 12.71±9.50 to 20.35±7.84 after the surgery(P=0.000).Postoperative KI scores of heart palpitation,sweating,sexual functioning,fatigue,nervousness,and depression were increased significantly in comparison with pre-operation(P0.05).Patients in Postpone the surgery group showed higher scores of nervousness,headache,and sexual functioning compared with those in Accept the surgery group(P0.05).Conclusions:Perimenopausal women may at increased risk of experiencing more serious climacteric symptoms after bilateral ovariectomy.Strict indication of ovariectomy should be recommended while performing gynecological operations in perimenopausal women.