Clinical comparison between adenomyosis and hysteromyoma

Objective To explore the preoperative diagnosis of adenomyosis by comparing the clinical characteristics of adenomyosis and hysteromyoma and investigating the application of ultrasonography B and laboratory tests. Methods Comparisons were made in age distribution, pathological history, clinical symptom, preoperative diagnosis, ultrasonic B test and serum CA125 level between two groups: 120 cases of adenomyosis and 120 cases of hysteromyoma selected randomly from patients treated in our hospital during past 5 years. Results Significant differences were not observed in incident rate for these two diseases among both groups of patients tested (P0.05). Both diseases are subject to occur for women at reproductive age and share some clinical manifestations such as menorrhagia and / or menostaxis. The preoperative diagnosis rate is 56.1% for adenomyosis. The characteristic symptoms of adenomyosis include more frequent algomenorrhae and dyspareunia, less likely secondary anemia, distinct characteristics in ultrasonography B, and the elevated selum CA125 levels. Conclusion Pathological diagnosis is the golden standard to diagnose adenomyosis, but pathological history, clinical symptom, change of ultrasonography B and the increased serum CA125 levels are important reference index to differentiate adenomyosis from hysteromyoma, particularly before the operation.