Subject Clinical observation on the menstrual disorder induced by antipsychotics

[Objective]To find out the disordered menstrual cycle of some female patients associated with the antipsychotics. [Methods]The article has looked into 129 patients altogether, 34 of them were given cholorpromazine, 29 were given clozapine, 18 were given resperidone and 48 were given a combination of the above medicines. Judgment was made on patients who have taken the medicine. Patients with abnormal menstrual cycle were observed with decreased amount of medicines in order to verify the relationship between the antipsychotics and the disordered menstrual cycle. [Results] among 387 menstrual cycles of 129 patients, the incidence of disordered menstrual cycle amount to 144. The main manifestation is the extension of the menstrual cycle, especially when the doctors utilize chlorpromazine or the combination of the antipsychotics on them. [Conclusion] Antipsychotics may induce the disorder of the menstrual cycle. Attention should be paid to this risk.