Clear Cell Carcinoma of the Ovary with Disseminated Intravascular Coagulation and Haemoperitoneum with Tumour Perforation

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Abstract

We report a case of a 34-year-old woman with haemoperitoneum and acute disseminated intravascular coagulation (DIC) following the rupture of ovarian clear cell carcinoma (OCCC), the first documented case of its kind. Although DIC is known to be associated with ovarian cancer, acute DIC with bleeding in the clear cell variant has not been reported. The patient, who had a right adnexal lesion, was found to have anaemia and thrombocytopenia. Intra-abdominal bleeding due to the rupture of a malignant ovarian cyst associated with DIC was identified as the cause. After surgery, the DIC resolved, suggesting that OCCC can be an aetiology for acute DIC and bleeding.

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License: CC-BY-4.0