MRgFUS for pain relief as palliative treatment in recurrent cervical carcinoma: a case report

R Machtinger, Machtinger R, Inbar Y, Y Inbar, Ben-Baruch G, G Ben-Baruch, Korach J, J Korach, Rabinovici J, J Rabinovici
Gynecologic Oncology · 2008 · doi:10.1016/j.ygyno.2007.08.079 · PMID:18028990
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This case report demonstrates that MRgFUS provided marked pain relief and improved performance status in a patient with recurrent cervical carcinoma, suggesting it as a safe palliative alternative to invasive techniques.

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Abstract

INTRODUCTION: Focused ultrasound under real-time MR guidance and control (MRgFUS) can be used for the thermal ablation of tissue. Currently this technique is used clinically for the noninvasive treatment of uterine leiomyomas and is in clinical evaluation for breast cancer, adenomyosis and other indications. MRgFUS is being tested for pain relief in patients suffering from bone metastases. This is the first case to report on MRgFUS for pain relief in patients suffering from recurrent cervical carcinoma. CASE REPORT: A 29-year-old patient with recurrent squamous cell carcinoma of cervix following radical hysterectomy, chemotherapy and radiation was treated by MRgFUS due to pelvic mass unresponsive to conventional treatment that caused intractable pain. Following two treatments the patient experienced a marked reduction in pain and increase in Karnovsky Performance Status (KPS) from 50% to 80%. DISCUSSION: Palliative treatment of pain with noninvasive MRgFUS in cases of recurrent cervical carcinoma may be a safe and efficient alternative to other invasive techniques.

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Condition tags

adenomyosis

MeSH descriptors

Carcinoma, Squamous Cell Intractable Pain Neoplasm Recurrence, Local Uterine Cervical Dysplasia Uterine Cervical Neoplasms Adult Carcinoma, Squamous Cell Carcinoma, Squamous Cell Carcinoma, Squamous Cell Female Humans Intractable Pain Intractable Pain Magnetic Resonance Imaging Neoplasm Recurrence, Local Neoplasm Recurrence, Local Ultrasonic Therapy Ultrasonic Therapy Ultrasonography Uterine Cervical Dysplasia

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