Cytomegalovirus excretion in pregnant and nonpregnant women

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Using PCR to detect cytomegalovirus-specific immediate-early gene sequences, researchers found that cervical and urinary excretion rates in pregnant Taiwanese women increased significantly as pregnancy progressed compared to nonpregnant controls.

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Abstract

Cervical and urinary excretion of cytomegalovirus by Taiwanese women was identified by the presence of a cytomegalovirus-specific immediate-early gene sequence amplified by the polymerase chain reaction. Excretion rates during the first trimester of pregnancy resembled rates for nonpregnant women. As pregnancy proceeded, the cervical excretion rate increased from 13 to 40% and the urinary excretion rate increased from 1 to 13%.

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MeSH descriptors

Cytomegalovirus Cytomegalovirus Infections Pregnancy Complications, Infectious Urine Adult Base Sequence Cervix Uteri Cervix Uteri Cytomegalovirus Cytomegalovirus Cytomegalovirus Infections Cytomegalovirus Infections DNA, Viral DNA, Viral Female Humans Molecular Sequence Data Polymerase Chain Reaction Pregnancy Pregnancy Complications, Infectious

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europepmc
last seen: 2026-11-01T09:25:17.647243+00:00
pubmed
last seen: 2026-10-08T21:59:31.578486+00:00
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