Cervikalna endometrioza – prikaz primera in pregled literature

In: Slovenian Medical Journal · 2022 · pp. 1–4 · doi:10.6016/zdravvestn.3238 · W4213329749
article OA: diamond CC0 ⤵ 1 in-corpus citation
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This case report and literature review discusses cervical endometriosis, a condition where endometrial tissue is found in the cervix, and details its presentation in a 32-year-old woman with contact bleeding and abnormal colposcopy.

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This paper presents a case report of a 32-year-old woman evaluated after contact bleeding and a pathologic colposcopy finding, along with a review of the literature on cervical endometriosis. It describes cervical endometriosis as ectopic endometrial glands and stroma in the cervix that commonly cause bloody vaginal discharge or extra cyclic bleeding, and notes that cervicovaginal smears can show endometrial gland cells that may resemble normal endometrial cells or atypical glandular cells of undetermined significance (AGUS), sometimes including adenocarcinoma in situ (AIS)-like patterns. The authors’ key caveat is that cytologic appearances can overlap with premalignant/malignant glandular lesions, creating interpretive pitfalls. This paper is centrally about endometriosis — it focuses specifically on cervical endometriosis and how it presents clinically and mimics atypia on cervicovaginal cytology.

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Abstract

Endometrioza je bolezen, pri kateri so endometrijske žlezne celice in stroma prisotni zunaj maternične votline. Kadar se endometrijske žleze in stroma nahajajo v materničnem vratu, govorimo o cervikalni endometriozi. Klinično se cervikalna endometrioza najpogosteje kaže kot krvav vaginalni izcedek ali izvenciklična krvavitev. Na brisih materničnega vratu (BMV) lahko endometrioza izgleda, kot da bi šlo za normalne endometrijske žlezne celice ali kot atipične neopredeljene žlezne celice (AŽC-N), vključno z adenokarcinomom in situ (AIS). Članek predstavi primer 32-letne ženske, ki je bila sprejeta na oddelek za ginekologijo zaradi kontaktnih krvavitev in patološkega izvida kolposkopije.
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Cervical enometriosis – a case report and review of literature DOI: https://doi.org/10.6016/ZdravVestn.3238Keywords: endometrial cells, cervicovaginal smear, atypical glandular cells of undetermined significance, cytology, histologyAbstract Endometriosis is a disease in which endometrial glandular cells and stroma are present outside the uterine cavity. When the endometrial glands and stroma are located in the cervix, this is called cervical endometriosis. Clinically, cervical endometriosis most commonly presents as bloody vaginal discharge or extra cyclic bleeding. On cervical smears (CS), endometriosis may look like normal endometrial gland cells or atypical glandular cells of undetermined significance (AGUS), including adenocarcinoma in situ (AIS). We report a case of a 32-year-old woman who was admitted to the gynaecology department due to contact bleeding and a pathological colposcopy result. Downloads References 1. Agarwal N, Subramanian A. Endometriosis - morphology, clinical presentations and molecular pathology. J Lab Physicians. 2010;2(1):1-9. DOI: 10.4103/0974-2727.66699 PMID: 21814398 2. Ata B, Ates U, Usta T, Attar E. Cervical endometriosis, a case presenting with intractable spotting. MedGenMed. 2005;7(2):64. PMID: 16369442 3. Laganà AS, Garzon S, Götte M, Viganò P, Franchi M, Ghezzi F, et al. The pathogenesis of endometriosis: molecular and cell biology insights. Int J Mol Sci. 2019;20(22):5615. DOI: 10.3390/ijms20225615 PMID: 31717614 4. Medeiros F, Cavalcante DI, Medeiros MA, Eleutério J. Fine-needle aspiration cytology of scar endometriosis: study of seven cases and literature review. Diagn Cytopathol. 2011;39(1):18-21. DOI: 10.1002/dc.21319 PMID: 20058306 5. Yokota N, Yoshida H, Sakakibara H, Inayama Y, Hirahara F. A severe vaginal hemorrhage caused by cervical endometriosis. Am J Obstet Gynecol. 2008;199(1):e12-3. DOI: 10.1016/j.ajog.2008.02.012 PMID: 18585517 6. 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DOI: 10.1002/dc.10418 PMID: 14755757 Downloads Published Issue Section License The Author transfers to the Publisher (Slovenian Medical Association) all economic copyrights following form Article 22 of the Slovene Copyright and Related Rights Act (ZASP), including the right of reproduction, the right of distribution, the rental right, the right of public performance, the right of public transmission, the right of public communication by means of phonograms and videograms, the right of public presentation, the right of broadcasting, the right of rebroadcasting, the right of secondary broadcasting, the right of communication to the public, the right of transformation, the right of audiovisual adaptation and all other rights of the author according to ZASP. The aforementioned rights are transferred non-exclusively, for an unlimited number of editions, for the term of the statutory The Author can make use of his work himself or transfer subjective rights to others only after 3 months from date of first publishing in the journal Zdravniški vestnik/Slovenian Medical Journal. The Publisher (Slovenian Medical Association) has the right to transfer the rights of acquired parties without explicit consent of the Author. The Author consents that the Article be published under the Creative Commons BY-NC 4.0 (attribution-non-commercial) or comparable licence.

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