Histologic classification of specimens from women affected by superficial endometriosis, deeply infiltrating endometriosis, and ovarian endometriomas

other OA: bronze public-domain-us
AI-generated summary by claude@2026-06, 2026-06-07

This study evaluated histologic differentiation in endometriosis lesions, finding superficial endometriosis predominantly well-differentiated, while deeply infiltrating endometriosis and ovarian endometriomas showed more undifferentiated and mixed glandular patterns.

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Abstract

In this retrospective observational study involving 176 patients and 271 biopsies, the histologic differentiation in superficial endometriosis, deeply infiltrating endometriosis, and ovarian endometriomas was evaluated according to a previously proposed classification system. Results showed a predominance of the undifferentiated glandular pattern (33.5%) and mixed glandular pattern (46.9%) in deeply infiltrating endometriosis lesions, whereas the well-differentiated glandular pattern (41.8%) was most frequently seen in superficial endometriosis lesions, and in ovarian endometriomas a predominance of both the undifferentiated (40.5%) and mixed patterns (37.8%) was observed.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Ovarian Diseases Ovarian Diseases Severity of Illness Index Adult Biopsy Endometriosis Endometrium Endometrium Female Humans Ovarian Diseases Ovary Ovary Prognosis Retrospective Studies Stromal Cells Stromal Cells

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Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
pubmed
last seen: 2026-05-13T22:14:05.573375+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine