GnRH-a and gestrinone to prevent endometrial endometriosis recurrence

Objective To observe efficacy and adverse effects and recurrence of GnRH-a and gestrinone in prevention of endometriosis.Methods A total of 149 patients in our hospital was hospitalized on June 2007 June 2009 by B ultrasound and surgical treatment of endometriosis patients were randomly divided into two groups of GnRH-a group of 96 cases,gestrinone group 53 cases,two groups were compared the efficacy and pregnancy rate of adverse reactions.Results Of GnRH-a group of remarkable efficiency,the rate of improvement with the control group the difference was not significant,but the GnRH-a group the recurrence rate was significantly lower than the control group,the difference was significant(P 0.05).r-AFS stage,phase Ⅰ,Phase Ⅱ in patients with pregnancy rate was significantly higher than in stage Ⅲ,Ⅳ patients,the difference was significant(P 0.01).GnRH-a group 1 case of weight gain,and one cases of vaginal dryness,and the incidence of adverse reactions was significantly lower than the gestrinone group.Conclusion GnRH-a to prevent endometriosis postoperative recurrence results were satisfactory,safe and reliable,low recurrence rate,the effective than gestrinone,is worthy of clinical use.