Excess healthcare costs of psychological distress in young women: Evidence from linked national Medicare claims data

Health economics · 2023 · vol. 32(3) , pp. 715–734 · doi:10.1002/hec.4641 · PMID:36495290 · PMC10947058
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Using Australian Medicare data, this study found that young women with psychological distress incur 15% higher annual healthcare costs than those without distress, driven primarily by mental health service utilization.

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This study utilizes linked Australian Medicare claims and longitudinal survey data to quantify the excess healthcare costs associated with psychological distress in women aged 18 to 27. The analysis reveals that severe psychological distress increases annual public healthcare spending by approximately $96 million for this demographic, driven primarily by higher utilization of mental health services such as psychologists and antidepressants. The findings indicate that these excess costs are most pronounced during the first six months following the onset of distress and remain robust across various econometric adjustments for selection bias and unobserved heterogeneity. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

The prevalence of mental health disorders in young adults is increasing, yet there is limited empirical evidence on its economic consequences. We contribute to the literature by estimating the healthcare costs of psychological distress using panel data of young women (aged 18-23 years with a 5-year follow-up) from the Australian Longitudinal Study on Women's Health and linked administrative data from Medicare Australia. Our empirical strategy is based on the classical two-part model of healthcare costs with individual specific fixed-effects. We complement our analysis with a test for selection on unobservables to address potential concerns of endogeneity. We find that young women with psychological distress have 15% higher annual healthcare costs (excluding hospital costs) than women with no psychological distress. A large proportion of these costs is driven by the use of antidepressants and the services of psychiatrists and psychologists. We further find that women with psychological distress have higher out-of-pocket costs on these mental health related services compared to non-mental health specific services. Additionally, we show that the effect of psychological distress on healthcare costs is highest during the first 6 months of onset, which gradually decreases afterwards. The findings justify the importance of policy initiatives towards early prevention and treatment of psychological distress, especially among young women.
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Data

Our data are from the Australian Longitudinal Study on Women's Health (ALSWH), which is an ongoing panel survey. This study uses data from the cohort born in 1989–95 of ALSWH which began in 2013 and was primarily recruited via the Internet and social media platforms (see Mishra et al. ( 2014 ) for detailed information on the study design and sample.) To date there are six waves of data collected annually and our analysis is based on an unbalanced panel of women observed from wave 1 in 2013 (aged 18–23) to wave 5 in 2017 (aged 22–27 years). After dropping respondents with missing data on variables of interest, our sample consists of 16,892 women with 53,449 person‐year observations. 2 We use the Kessler Psychological Distress Scale (K10) to construct our measure of psychological distress. The K10 scale is an internationally validated screening instrument of psychological distress, based on 10 questions (Kessler et al.,  2002 , 2003 ). As a self‐reported measure, it reports how often the respondent experienced psychological distress (such as feelings of worry, anxiety, hopelessness and unhappiness) during the past 4 weeks. 3 All questions include five response categories from 1 to 5 (1 = none of the time; 2 = a little of the time; 3 = some of the time; 4 = most of the time and 5 = all of the time). The K10 score is calculated by obtaining the sum of the 10 responses. This ranges from 10 (no psychological distress) to 50 (severe psychological distress), meaning a higher score reflects a higher level of psychological distress. In general, a score greater than 24 is considered as an indication of a high level of psychological distress (Cornelius et al.,  2013 ). In our analysis we further adopt the following cut‐off scores to categorize women into four levels; no psychological distress (10–19); mild psychological distress (20–24); moderate psychological distress (25–29) and severe psychological distress (30–50) (Yiengprugsawan et al.,  2014 ). In addition to the K10 score, there are two measures of depression self‐reported in all waves, except wave 4 (2016). First, a binary indicator refers to whether the individual has been ever diagnosed with or treated for depression. Second, a multi‐item indicator where the individual reports how often they had depression in the last 12 months; (1) never; (2) rarely; (3) sometimes and (4) often. Since K10 assesses mental health symptoms related to depression and anxiety (Kessler et al.,  2002 ), we use both these alternate measures as robustness checks (see Section  5 ). Figure  1 illustrates the distribution and dynamics of the K10 score for the pooled sample of women (age 18–27). Almost half of the women (47%) have a score of less than 20 indicating no significant feelings of distress. The percentage of women with mild, moderate and severe psychological distress are 21%, 14% and 18% respectively (Panel A). Panel B shows the dynamics in K10 score by age. K10 score shows a gradual decrease as women get older. The K10 score peaks at a score of 23 when the women are younger (18–23 years) and reduces to a score of 21 after 5 years (22–27 years). Similarly, the percentage of women with no psychological distress increases from 42 to 52 over the 5 years while the percentage of women with severe psychological distress decreases from 22 to 14. 4 Distribution and dynamics in K10 score. Authors' illustration based on data from the cohort born in 1989–95 of the ASLWH survey. The dotted lines present the cut‐off points for the levels of psychological distress; no psychological distress (<20), mild psychological distress (20–24), moderate psychological distress (25–29) and severe psychological distress (≥30). Data on healthcare costs are extracted from the linked administrative records of Medicare Australia. Medicare is a universal public health insurance scheme that provides free or subsided healthcare access to all individuals who reside permanently in Australia. The Medicare records include complete data on medical services, which are eligible for rebate through the Medicare Benefits Schedule (MBS) and prescription medications subsidized through the Pharmaceutical Benefits Scheme (PBS). Several broad categories of medical services are covered under the MBS which includes consultations by general practitioners (GPs), practice nurses, specialists, allied health professionals and other outpatient services such as pathology, diagnostic and imaging, optometry, among many others. However, allied health and specialist attendances are the key categories that include a majority of the mental health related services. Particularly, specialist attendances capture items corresponding to consultations by psychiatrists, and allied health includes psychological services provided by clinical psychologists, psychologists, occupational therapists and social workers, introduced under the Better Access to Mental Health Care initiative in 2006. 5 The MBS also covers hospital services provided only to private patients. Since it does not capture inpatient services for public patients, we exclude all MBS records of hospital services to maintain consistency. Therefore, our measure of total healthcare cost (or Medicare cost) is the summation of annual costs incurred by each woman for non‐hospital medical services under MBS and pharmaceuticals listed under PBS. 6 All costs are in 2019 Australian dollars (AUD) adjusted for inflation. Figure  2 shows the non‐parametric estimates of the association between K10 score and total healthcare costs. The figure depicts a somewhat linear relationship between K10 score and costs, where the costs increase gradually with an increase in K10 score. Compared to the range of no psychological distress, the variation in costs becomes steeper with each level of symptoms. This implies that the effect of psychological distress on healthcare costs is progressive with each level. Non‐parametric regression of healthcare costs on K10 score. Data is for the pooled sample (age 18–27), N  = 53,449. Total costs includes both MBS and PBS costs, and are in 2019 Australian dollars. The dotted lines present the cut‐off points for the levels of psychological distress; no psychological distress (<20), mild psychological distress (20–24), moderate psychological distress (25–29) and severe psychological distress (≥30). Table  1 shows the distribution of healthcare costs by levels of psychological distress for the pooled sample. The mean annual total healthcare cost in the full sample is $1198, and it varies with the level of psychological distress categories (Panel A). Women with severe psychological distress incur $1802 per year as Medicare costs, which is almost double the costs of women with no psychological distress. Women with moderate and mild psychological distress incur an additional $409 (43%) and $187 (20%) than women with no psychological distress respectively. A similar pattern is observed for total MBS (medical services) costs. However, for specific MBS items, mean costs for specialist and allied attendances are considerably greater for women in moderate and severe psychological distress. Specifically, women with severe psychological distress incur three to five times higher costs for total specialist and allied items, compared to women with no psychological distress. This may be due to the utilization of psychiatrists and psychologists, which are captured under specialist and allied health categories. Mean healthcare costs by levels of psychological distress Note : Total healthcare costs includes both MBS and PBS costs. All costs are in 2019 Australian dollars. Abbreviations: GP, general practitioners; MBS, Medicare Benefits Schedule; PBS, Pharmaceutical Benefits Scheme. Panel B reports the proportion of women with non‐zero spending on Medicare services. Based on the full sample, in any given year, 97% of the women aged 18–27 have positive spending. Young women are more likely to use MBS services than PBS, since 97% of the women have positive MBS costs, while only 82% incur PBS costs. A substantial proportion of women do not incur any annual costs on specialist and allied health services, and this is particularly pronounced at the lower levels of psychological distress. When considering the women who have had positive spending (Panel C), the mean total Medicare cost is $1232. For specific MBS items, the mean cost is highest for allied health attendances ($690) followed by specialist attendances ($503). To control for potential confounding factors, we consider several covariates that are commonly used in estimating the healthcare costs of mental disorders. This includes age, highest level of education (indicator variables for grade 10 and below, grade 11, grade 12, certificate, diploma, degree and post‐graduate), employment status (unemployed or not unemployed), income (proxied by the ability to manage income and access to government healthcare card) and marital status (never married, married, de‐facto, separated and divorced) (Bodden et al.,  2018 ; Hsieh & Qin,  2018 ; Lucas et al.,  2013 ). 7 We also consider regional and state heterogeneity, by including residence and state dummy variables. Finally, we include year dummies in all the regression models. Descriptive statistics are presented in Table  S2 . The average age is 22 years and the majority of the women (70%) are not married. Thirty‐five percent have either a degree or a post‐graduate qualification, which is comparable to national estimates (ABS,  2020a ). Approximately 75% of the women live in a metro area, compared to regional and rural, and this is a broad representative of the geographical distribution of the population (Mishra et al.,  2014 ). Almost 30% have access to a healthcare card. Table  S2 also displays the descriptive statistics by each level of psychological distress. Women with moderate and severe psychological distress are on average less educated, more likely to be unemployed and find it difficult to manage income, compared to women with no psychological distress, indicating the socioeconomic gradient in mental health (Byles et al.,  2012 ; Hammarström et al.,  2011 ; Kosidou et al.,  2011 ).

Empirical

We first examine the effect of psychological distress on total healthcare costs (or Medicare costs) which is the summation of annual costs incurred on both medical services (MBS) and pharmaceuticals (PBS). Table  2 presents the empirical results based on the two‐part model (Equations  1 and 2 ). Columns (1) and (2) report the coefficient estimates from the linear individual fixed‐effects model. The effect of K10 score on the probability of incurring any Medicare costs is positive and significant. With regard to the amount of healthcare cost, an increase in K10 score by one unit increases the conditional cost by 1.6% (column 2). Considering an indicator variable for psychological distress, compared to women with no psychological distress, those with psychological distress have 15% higher healthcare costs (column 2 of Panel B). Panel C shows that the effect of psychological distress on costs increases substantially with each level of symptoms. Specifically, women with moderate psychological distress have 15% higher healthcare costs, than women with no psychological distress. The effect is much larger for women with severe psychological distress, where the conditional cost increases by 26% (column 2 of Panel C). All coefficients are statistically significant at 1%. Coefficient estimates of the effects of psychological distress on healthcare cost Note : Robust standard errors in parenthesis, clustered at individual level. All regression models control for age, marital status, education, employment, income management, access to healthcare card, residence, state and year dummies. Positive costs denote the extensive margin of healthcare costs, while log costs denote the intensive margin, conditional on incurring any healthcare costs. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. For comparison, the random‐effects (RE) estimates of the two‐part model are reported in columns (3) and (4) respectively. Similar to within‐individual fixed‐effects model, the effects on both the extensive and intensive margin of healthcare costs are positive and highly significant. However, the effects are much larger in size to the FE estimates. For further comparison, we present the OLS estimates in columns (5) and (6), which are considerably larger than both FE and RE estimates. The smaller FE estimates compared to OLS and RE estimates suggest the presence of unobserved confounders at the individual level, causing an over‐utilization of healthcare services (positive selection bias). This may be due to several reasons such as; (1) positive personality traits, attitudes and habits towards a healthy lifestyle which are correlated with a lower likelihood of psychological distress and a higher use of healthcare services (due to regular medical check‐ups and health screening), (2) family history of mental health problems (genetic endowments) leading to both higher likelihood of distress and healthcare costs, (3) high health expectations causing young women to assess a health condition negatively (Bago d’Uva et al.,  2008 ), and thereby a greater use of healthcare services. 9 The actual marginal/incremental healthcare costs of psychological distress are shown in Table  3 . The conditional predicted costs in dollar scale are estimated from equation two of the two‐part model. The unconditional predicted costs are derived by multiplying the predicted probabilities and costs from each part of the two‐part model. We apply the Duan ( 1983 ) smearing estimator to transform predictions of log expenditures into its levels. Since healthcare costs vary by the levels of distress, we use separate smearing factor by K10 scores to account for its heteroskedasticity (Manning & Mullahy,  2001 ). On average, a one‐unit increase in K10 score increases annual unconditional healthcare costs by $18. Considering an indicator variable for psychological distress, on average, women with psychological distress have higher total healthcare costs of $179 than women with no psychological distress (Panel B column 2). As seen in Table  2 , the incremental unconditional effect of psychological distress on costs increases with the severity of distress. In particular, women with mild, moderate or severe distress have higher healthcare costs of $93, $179 and $310 than women with no symptoms of distress respectively. Tables  1 and 2 indicate that the higher healthcare costs of psychological distress are primarily due to an increase in spending by women with positive spending, rather than an increase in the probability of spending. This is plausible given that almost 97% of women have a positive cost on healthcare services. Conditional and unconditional marginal/incremental effects of psychological distress on healthcare cost (dollars) Note : The conditional costs are the marginal/incremental effects in dollar scale estimated from the second part of the model. The unconditional predicted costs are derived by multiplying the predicted probabilities and costs from each part of the two‐part model. Bootstrapped standard errors in parenthesis. Duan smearing factor by K10 scores is used to transform predictions of log expenditures into its levels. All costs are in 2019 Australian dollars (AUD) and adjusted for inflation. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. The FE estimates reported in Table  2 may be biased if there is selection on unobservables. To assess the extent of bias caused by unobservable characteristics we use Oster ( 2019 ) method. Panel B of Table  4 reports the results. The baseline effect (FE estimate without controls) and controlled effect (FE estimate with all controls) are quite similar, implying that once we account for time‐invariant heterogeneity there is minimum time‐varying selection bias. This is further reassured by the magnitude of delta ( δ ). For both measures of psychological distress (K10 score and distress dummy), values of δ are almost zero under both R max assumptions. 10 Further, the bias‐adjusted effects assuming δ  = 1 are identical to the FE estimates. This suggests that the unobservables or omitted variables are less influential in explaining the effect of psychological distress on healthcare costs than the included controls. Estimates from Oster method Note : Robust standard errors in parenthesis, clustered at individual level. Controls include age, marital status, education, employment, income management, access to healthcare card, residence, state and year dummies. The estimates on conditional costs obtained from the linear model of log costs are reported. N  = 51,957. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. Overall, the results in Table  4 imply that omitted variable bias is not likely to bias the FE estimates. Therefore, we proceed with the two‐part model with individual fixed‐effects as our preferred model of estimation for the remaining analysis. In this section, we investigate whether the effect of psychological distress is heterogeneous by main types of Medicare cost; health services use (MBS) and pharmaceuticals (PBS). Table  5 reports the FE coefficient estimates from the two‐part model. An increase in K10 score by one unit increases the conditional MBS and PBS costs by 1.6% and 0.9% respectively. Considering indicator variables, young women with moderate and severe psychological distress have 16 and 28% higher costs on MBS medical services respectively, than women with no psychological distress. The estimates are smaller for PBS services, as moderate and severe psychological distress lead to a corresponding increase of 8 and 14%. Table  6 presents the marginal/incremental effects of psychological distress on MBS and PBS costs. The unconditional costs on MBS and PBS increase by $13 and $2 respectively as the K10 score increases by one unit. Moreover, women with moderate and severe psychological distress incur $128 and $226 higher unconditional costs on MBS medical services, which is considerably larger than costs on PBS medications. These findings imply that the use of MBS medical services contributes to a higher proportion of total healthcare costs of psychological distress. Coefficient estimates of the effects of psychological distress by type of Medicare cost Note : Robust standard errors in parenthesis, clustered at individual level. All regression models control for age, marital status, education, employment, income management, access to healthcare card, residence, state and year dummies and individual fixed‐effects. Positive costs denote the extensive margin of healthcare costs, while log costs denote the intensive margin, conditional on incurring any healthcare costs. Abbreviations: MBS, Medicare Benefits Schedule; PBS, Pharmaceutical Benefits Scheme. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. Conditional and unconditional marginal/incremental effects of psychological distress by type of Medicare cost (dollars) Note : The conditional costs are the marginal/incremental effects in dollar scale estimated from the second part of the model. The unconditional predicted costs are derived by multiplying the predicted probabilities and costs from each part of the two‐part model. Bootstrapped standard errors in parenthesis. Duan smearing factor by K10 scores is used to transform predictions of log expenditures into its levels. All costs are in 2019 Australian dollars (AUD) and adjusted for inflation. Abbreviations: MBS, Medicare Benefits Schedule; PBS, Pharmaceutical Benefits Scheme. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. Given the higher use of MBS medical services, it is useful to examine which specific MBS categories drive the total healthcare costs of psychological distress. The FE coefficient estimates presented in Table  7 indicate that women with psychological distress have higher costs on allied attendances, followed by specialist and GP attendances. Specifically, a one unit increase in K10 score increases the conditional costs of allied, specialist and GP visits by 2.3%, 1.4% and 1.2% respectively. A similar pattern is observed even if we use indicator variables to denote levels of psychological distress (Panel B). Women with severe psychological distress have 41% higher conditional costs on allied attendances than women with no psychological distress, which is nearly double the additional costs they incur on specialist (25%) and GP attendances (21%). However, when considering the marginal/incremental effects in Table  8 we observe that compared to conditional costs, the unconditional costs specifically on allied health and specialist attendances are smaller. This is because a substantial proportion of women (more than 75%) have zero positive costs on these services. Moreover, as we would expect, both K10 score and the dummy variables for psychological distress do not have a significant effect on the conditional costs of other MBS categories such as imaging, operations, optometry and other services, as reported in Table  S3 . Coefficient estimates of the effects of psychological distress on various MBS items Note : Robust standard errors in parenthesis, clustered at individual level. All regression models control for age, marital status, education, employment, income management, access to healthcare card, residence, state and year dummies and individual fixed‐effects. Positive costs denote the extensive margin of healthcare costs, while log costs denote the intensive margin, conditional on incurring any healthcare costs. Abbreviations: GP, general practitioners; MBS, Medicare Benefits Schedule. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. Conditional and unconditional marginal/incremental effects of psychological distress on various MBS items (dollars) Note : The conditional costs are the marginal/incremental effects in dollar scale estimated from the second part of the model. The unconditional predicted costs are derived by multiplying the predicted probabilities and costs from each part of the two‐part model. Bootstrapped standard errors in parenthesis. Duan smearing factor by K10 scores is used to transform predictions of log expenditures into its levels. All costs are in 2019 Australian dollars (AUD) and adjusted for inflation. Abbreviations: GP, general practitioners; MBS, Medicare Benefits Schedule. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. We now examine whether the onset of psychological distress will have a different effect to having psychological distress on healthcare costs. We define onset of psychological distress as the first reporting of psychological distress (i.e., a K10 score >24) preceded by no psychological distress in previous waves (Pan et al.,  2020 ). For this purpose, we first restrict our sample to a balanced panel. Next, we drop those women who have psychological distress in all five waves and women with psychological distress in the first wave. To capture chronicity of psychological distress, we create dummy variables based on the number of times the women have psychological distress throughout the five waves. That is we estimate three alternate models using psychological distress defined as only if they have it in (1) at least 2 waves, (2) at least 3 waves, and (3) in all four waves. Fixed‐effects estimates reported in Table  9 show that an onset of psychological distress (at least in one wave) increases the healthcare costs by 17%. This is slightly larger than the baseline estimate of 15% from the complete unbalanced sample reported in Table  2 . As anticipated, persistent psychological distress leads to higher conditional healthcare costs. Specifically, women with psychological distress in at least 2, 3 and all 4 waves have 21%, 28% and 25% higher healthcare costs respectively, than women with no psychological distress. 11 Coefficient estimates of the effects of onset and chronicity of psychological distress on healthcare costs Note : Robust standard errors in parenthesis, clustered at individual level. All regression models control for age, marital status, education, employment, income management, access to healthcare card, residence, state and year dummies and individual fixed‐effects. Positive costs denote the extensive margin of healthcare costs, while log costs denote the intensive margin, conditional on incurring any healthcare costs. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. The measurement of psychological distress based on the K10 score can reflect a short‐term phenomenon as it reports on the symptoms during the past four weeks (Lebenbaum et al.,  2021 ). This reference period is much shorter than the reference period for the outcome of interest (annual healthcare costs), resulting in a timing mismatch. As this is likely to underestimate the true effect of psychological distress on healthcare costs, we investigate whether the effect varies with the time‐period under consideration. In this regard, we estimate the effect on derived monthly healthcare costs by using the month of the survey returned of each individual as the starting point. For instance, if a woman has returned the survey during the month of May in a given year, we match the Medicare records of that particular month to estimate the total costs incurred during the first month (T1) since the occurrence of psychological distress. The total costs for 2 months (T2) is obtained by adding the costs incurred in May and June while the total cost for 3 months (T3) is the summation of costs in May, June and July. We follow this pattern until T12, which represents the total costs for the period of 12 months from the survey returned month. The estimates from the two‐part model on derived monthly healthcare costs are shown in Table  S4 and the effects of K10 score on conditional costs are summarized graphically in Figure  3 . According to Panel A, the effect of K10 score on total healthcare costs is highest at the 3 month period (about 2%) which then decreases gradually to 1.5% at the 12‐months period. On average these effects tend to vary within the range of 1.5–2.0% and are quite similar to the estimate from the FE model on annual costs (1.6%) indicated by the dashed line. We observe a similar pattern for the two types of Medicare costs; MBS and PBS services, where the effect of psychological distress tend to be highest during the first 6 months compared to the last 6 months since reporting of symptoms. Monthly variation in healthcare costs. The effects represent the estimates obtained from the second part of the model on conditional monthly costs, which are statistically significant at 1% level. All estimations control for age, marital status, education, employment, income management, access to healthcare card, residence, state and time dummies and individual fixed‐effects. The dashed lines indicate the corresponding estimates obtained from the two‐part model on conditional annual costs. Panel B illustrates the effects of K10 score on monthly healthcare costs by types of specific MBS categories. When considering costs on allied attendances, there is a substantial spike in the effect from T1 to T2 period, which then fluctuates within the range of 1.8–2.3%. The effects on costs of specialist attendances also show an oscillating pattern, which is highest during the period of three to 5 months since onset. Given that the monthly effects on average are very much similar to the estimates obtained from the annual costs, we believe there is minimum measurement error bias due to timing mismatch of reporting of psychological distress and healthcare costs. We now turn to estimate the effect of psychological distress on out‐of‐pocket (OOP) healthcare costs, as previous studies show a higher burden among those with depression (Callander et al.,  2017 ; Harman et al.,  2004 ; Rajan et al.,  2020 ). Table  10 presents the FE estimates from the two‐part model. A one‐unit increase in K10 score increases the conditional OOP costs on total healthcare services by 1.5%. We further observe that women with psychological distress have higher OOP expenditure on medical services covered by MBS (1.7%) than on PBS pharmaceuticals (1%). In terms of the indicator variable, young women experiencing psychological distress have 16 and 8% higher OOP costs on MBS and PBS services respectively, than women who do not experience psychological distress. Coefficient estimates of the effects of psychological distress on out‐of‐pocket healthcare costs Note : Robust standard errors in parenthesis, clustered at individual level. All regression models control for age, marital status, education, employment, income management, access to healthcare card, residence, state and year dummies and individual fixed‐effects. Positive costs denote the extensive margin of out‐of‐pocket healthcare costs, while log costs denote the intensive margin, conditional on incurring any out‐of‐pocket healthcare costs. *** p  < 0.01, ** p  < 0.05, * p  < 0.1. Considering higher OOP costs on MBS medical services, we investigate whether these OOP costs are driven by mental health specific services or other medical services. Table  11 shows that women with psychological distress have higher OOP costs for mental health‐related allied services (such as clinical psychologists, psychologists, and occupational therapists) and specialist services (consultant psychiatrists). A one unit increase in K10 score increases the total OOP costs on allied and specialist mental health related services by 2.1% and 1.6% respectively. Interestingly, there is no statistically significant effect on OOP costs related to other (non mental health specific) allied and specialist services. The findings are consistent even if we use an indicator variable to denote psychological distress. Women experiencing psychological distress have 21% higher OOP costs for allied and specialist mental health related services, than women with no psychological distress. Overall, this indicates that mental health related services are the main source of higher OOP costs among women with psychological distress. 12 Coefficient estimates of the effects of psychological distress on mental health and non‐mental health specific out‐of‐pocket healthcare costs Based on our predicted unconditional incremental effects from the FE model, we extrapolate the results to the Australian population to calculate the aggregate costs attributable to psychological distress among young women. There are approximately 1.72 million women aged 18–27 years in Australia (ABS,  2020b ), of whom about 21% have mild psychological distress, 14% have moderate psychological distress and 18% have severe psychological distress (estimates from ALSWH). Table  12 reports the extrapolated cost estimates, which we obtain by multiplying the average predicted extra cost per woman in each level of psychological distress (as shown in Table  3 , Panel C Column 2) by the total population of mild, moderate and severe psychological distress. We find that for women aged 18–27 years, compared to women with no psychological distress, the additional healthcare cost attributable to mild, moderate and severe psychological distress is approximately $33.66 million, $43.19 million and $96.17 million respectively. Annual healthcare cost attributable to psychological distress among women aged 18–27 Note : The healthcare costs include both MBS and PBS costs. Average excess cost per woman in each level is from the unconditional incremental effects shown in Table  3 .

Conclusion

The ongoing increase in the prevalence of psychological distress in young adults is a global concern. However, there is limited evidence on the magnitude of this issue in monetary terms. We contribute substantially to this space, by estimating the healthcare costs attributable to psychological distress using Australian longitudinal survey and administrative data. We find that moderate and severe psychological distress are associated with 15 and 26% higher healthcare costs compared to no psychological distress. Policy‐wise, our findings underscore the importance of providing affordable and accessible mental health services, especially targeting young women.

Discussion

Mental illness such as depression in young adults is a global health issue leading to health, economic and social consequences (WHO,  2008 ). While previous studies show a positive association between youth depression and healthcare costs, the magnitude of its impact on healthcare cost remains relatively unexplored (Bodden et al.,  2018 ). This study addresses this important issue, by using nationally representative survey data linked to administrative Medicare records from Australia. The use of national Medicare claims data allows to estimate precise government‐funded healthcare costs attributable to psychological distress. It is important to note that though our analysis does not fully address the causality claims, we still attempt to address certain key endogeneity issues that are usually prevalent in similar studies. Our preferred identification strategy is based on the classical two‐part model of healthcare costs with individual specific fixed‐effects, where we show that once we account for time‐invariant heterogeneity, there is minimum time‐varying selection bias. We further address the concern of omitted variable bias by applying Oster ( 2019 ) method for selection on unobservables. The analysis using monthly data provides suggestive evidence that reverse causality or simultaneity bias is also unlikely to bias our estimates. This is because the measure of healthcare costs is derived based on the months following the reporting of psychological distress. In addition, we also examine the sensitivity of our estimates to attrition bias and measurement error. However, given that we do not account for time‐varying unobservables and simultaneity bias fully, we caution against a strict causal interpretation. We find that women with moderate psychological distress have 15% higher healthcare costs, than women with no psychological distress. The effect is much larger for women experiencing severe psychological distress, where costs increase by 26%. We further find significant heterogeneity on several dimensions, such as persistence of the psychological distress and short and long‐term effects since the occurrence of the symptoms. To validate our findings, we exploit the richness of the administrative data on Medicare records to investigate whether the higher healthcare costs are in fact driven by the use of mental health related services. To this end, we examine the percentage utilization of specific mental health related MBS and PBS items compared to all other items by levels of psychological distress, which is summarized in Table  S8 . The use of mental health items increases with each level of psychological distress. Notably, when considering specialist attendance, the highest uptake of consultant psychiatrist items is among the women with severe psychological distress, which is almost 50% of their total specialist attendances. Similarly, out of total allied attendances, almost 84% are either for clinical psychologist or psychologist items coming under the Better Access to Mental Health Care program. We further look at the use of mental health related medications based on the Anatomical Therapeutic Chemical (ATC) codes. 16 The use of mental health related ATC codes is highest among women with severe psychological distress (44%) followed by women with moderate psychological distress (34%). A larger proportion of the total use is through the use of antidepressants. This provides support that mental health related services are the main source of excess costs of psychological distress in general. Extrapolating our results to the total population of women aged 18–27 years in Australia indicates that the additional healthcare cost attributable to moderate and severe psychological distress is approximately $139 million. To put this value into perspective, this represents 7% of the Australian government spending of 1966 million on Medicare subsidized mental health specific services and mental health‐related prescriptions under the PBS/RPBS in 2019/20 (AIHW,  2021 ). Our study has some data limitations. First, our sample of women (1989–95 cohort of ALSWH) may represent a convenience sample, as women were recruited using the Internet and social media platforms. This suggests that there is potential for selection along observable characterizes such as education and health status. However, Mishra et al. ( 2014 ) show that this cohort of women is a broadly representative sample of the Australian population based on a comparison of sociodemographic and health characteristics with comparable Australian Census and Health Survey data. Second, the K10 measure of psychological distress is based on self‐reported assessments, which may lead to measurement error (Frijters et al.,  2014 ; Lebenbaum et al.,  2021 ). 17 According to Bago d’Uva et al. ( 2008 ), young women are more likely to have high health expectations and thereby to assess a health condition negatively, implying an over‐reporting of symptoms. The use of individual fixed‐effects can account for such systematic heterogeneity in the self‐reporting of mental health. To further mitigate the concern of reporting bias, we consider alternative measures of depression based on diagnosed/treated for depression and show that the estimates are quite similar. Third, the Medicare data used in our analysis exclude all hospital costs due to the unavailability of public hospital records. This suggests that the effect of psychological distress on total Government healthcare costs may be underestimated. However, when considering mean differences of costs between women with psychological distress and no psychological distress, the magnitude of the difference is quite similar to other studies that report mean differences of various mental health disorders on total costs including hospital services (Bock et al.,  2016 ; Ride et al.,  2019 ). This implies that the omission of hospital costs is less likely to affect the estimated effect. 18 Our findings have significant policy implications. The prevalence of psychological distress is increasing, particularly among young adults (Burns et al.,  2020 ; Butterworth et al.,  2020 ; Twenge et al.,  2019 ). Our results show that the excess healthcare costs of psychological distress in young women in Australia are substantial, amounting to AUD 139 million annually. Given that psychological distress can lead to major mental health illnesses such as major depression (Horwath et al.,  1992 ), which further aggravate the burden on healthcare resources (Ride et al.,  2019 ), our findings highlight the importance of policy initiatives aimed at early intervention and prevention. We further find that women with psychological distress incur higher out‐of‐pocket costs on mental healthcare (specifically for services provided by consultant psychiatrists, clinical psychologists and psychologists) than on non‐mental health services. This suggests that higher costs may hinder young individuals from accessing required care, necessitating policy interventions to make mental healthcare affordable, particularly for young women. Such policy measures would inevitably reduce not only the economic consequences of psychological distress, but also the larger costs of other mental illnesses.

Robustness

We conduct several sensitivity checks to examine the robustness of our findings. First, we use a balanced panel to identify whether our estimates are affected by sample attrition bias. Table  S6 reports the results. The coefficients from the balanced panel for both extensive and intensive margin of healthcare costs are slightly larger compared to estimates from the unbalanced panel reported in Table  2 . The differences in the magnitude of the effects on conditional costs from the balanced and unbalanced panels are small (approximately 0.1% for the K10 score and two percent for the dummy variable on psychological distress), indicating the estimates are less likely to be affected by potential biases from sample attrition. 13 Second, we assess the validity of K10 score as a reliable measure of psychological distress. In this regard we consider two alternative measures of depression based on two different questions in ALSWH survey; (1) Have you ever been diagnosed with or treated for depression; and (2) In the last 12 months, have you had depression. Specifically, we estimate two separate equations with a dummy variable for diagnosed/treated for depression (=1 if marked yes, and 0 otherwise) and another dummy variable for depression in last year (=1 if answered sometimes or often, and 0 otherwise). It is important to note that these two questions are not included in Survey 4, and therefore the FE estimates from the two‐part model reported in Table  S7 are based on an unbalanced panel created using data from waves 1, 2, 3 and 5. For comparison, we also report the results obtained using a dummy variable for psychological distress based on the K10 score (Panel A, columns 1 and 2). The estimates using dummy variables derived from K10 score and felt depression in the past year are quite similar, as both suggest that women with psychological distress/depression have 15–16% higher costs. However, estimates using the dummy variable based on diagnosed/treated depression show almost a 19% increase in costs. This is expected as diagnosed/treated depression may be of chronic nature when compared to depression based on a symptom scale such as K10 score or depression feelings (Lebenbaum et al.,  2021 ), and thus leading to a higher effect on healthcare costs. Third, our main model does not include health status or other health conditions because these could be potentially correlated with psychological distress. However, there might be concerns about the validity of the estimates if these conditions have an independent and significant effect on healthcare utilization, causing potential omitted variable biases (Black et al.,  2018 ). To allay this concern, we re‐estimate our two‐part model including indicators for health status and conditions such as low iron, asthma, endometriosis and polycystic ovary syndrome (PCOS). 14 The estimates reported in Panel B of Table  S7 show that even after controlling for these conditions the effect of psychological distress on intensive margin of healthcare costs is still statistically significant at 1% and is quite similar to those reported in Panel A. This provides support that physical health conditions are less likely to drive the effect of psychological distress on healthcare costs. 15

Methodology

The classical two‐part model of healthcare costs (Jones,  2000 ; Mullahy,  1998 ) forms the basis of our empirical model. The first part of the model estimates the probability of incurring positive healthcare costs (extensive margin), while the second part estimates the effect on costs, conditional on incurring any (intensive margin). 8 The model is specified as; (1) P o s i t i v e C o s t s i t = α 1 + β 1 K 1 0 i t + η 1 X i t ′ + φ 1 i + γ 1 t + ε 1 it (2) L o g C o s t s i t | P o s i t i v e C o s t s i t > 0 = α 2 + β 2 K 1 0 i t + η 2 X i t ′ + φ 2 i + γ 2 i + ε 2 it where PositiveCosts it takes the value of 1 if woman i has non‐zero costs for Medicare services in year  t and 0 if the woman has zero costs. LogCosts it is the logarithm of healthcare costs incurred by woman i in year  t . K 10 it is the measure of psychological distress based on K10 score for each women woman i in year  t . We estimate separate models considering K10 score as a continuous variable and dummy variables for each level of psychological distress (i.e., mild, moderate and severe) with no psychological distress as reference category. X it is a vector of observable characteristics representing age, education, employment status, income, marital status and residence of woman i in year  t . φ i and γ t denote unobservable individual and year fixed effects respectively, and ɛ it is the error term. Throughout the analysis, both equations are specified as linear panel data models, and standard errors are clustered at the individual level and adjusted for heteroskedasticity. A key strength of the above model is the inclusion of φ i which captures all unobserved time‐invariant individual‐specific effects that are correlated with psychological distress. Some examples are, systematic heterogeneity in the reporting of mental health (Bago d’Uva et al.,  2008 ), genetic predisposition (Arango et al.,  2018 ) or habits such as substance misuse and addiction that are correlated with distress (American Psychiatric Association,  2013 ) but are unobserved. The use of fixed‐effect (or within) estimator (FE) eliminates these sources of bias when estimating β —the effect of psychological distress on Medicare costs. However, one caveat of the FE method is that it can lead to biased estimates in the presence of time‐variant unobserved heterogeneity. This may include financial wellbeing, level of health literacy and social stigma, which are associated with both psychological distress and utilization of healthcare services, causing omitted variable bias. To explore the extent of bias caused by selection on such unobservables, we apply the method of Oster ( 2019 ). Considering both coefficient and R ‐squared movements, this approach allows to calculate the degree of proportionality between observed and unobserved variables denoted as delta ( δ ), and thereby estimate the bias‐adjusted effect of psychological distress on healthcare costs. In principle, δ  = 1 suggests equal importance of both observables and unobservables. If δ is closer to zero the unobserved factors are less important than the observed factors, indicating the stability of coefficients (Oster,  2019 ).

Introduction

Mental health disorders are a global health issue where 1 in 10 individuals are affected by a mental illness, accounting for 792 million people worldwide (Ritchie & Roser,  2018 ). Among them, depression is one of the most common mental health disorders which has the third highest burden of disease globally (WHO,  2008 ), as well as in Australia (AIHW,  2014 ). Although depression can affect individuals during all stages of life, the highest prevalence is seen among young people (Beirão et al.,  2020 ; Productivity Commission,  2020 ; Schubert et al.,  2017 ), especially among young women, as they are twice as likely as men to develop depression (Hyde et al.,  2008 ; Kessler,  2003 ; Seedat et al.,  2009 ). Moreover, compared to older adults, the proportion of young people experiencing psychological distress has shown a significant increase over the past decade (Burns et al.,  2020 ; Butterworth et al.,  2020 ; Twenge et al.,  2019 ). Given the ongoing rise of psychological distress in young adults, quantifying the healthcare costs attributable to it is important. On the one hand, it is a starting point to signify the magnitude of the problem in terms of monetary terms (Productivity Commission,  2020 ), while on the other, it provides insights to estimate and predict the current and future economic burden of severe mental disorders. Further, it also provides evidence for policy makers to assess the economic return associated with interventions for prevention and treatment of mental illness (Lee et al.,  2017 ). However, despite such importance, the healthcare consequences of poor mental health in young adults remain relatively unexplored (Bodden et al.,  2018 ; König et al.,  2020 ). The literature on the economic costs of mental disorders is vast. For instance, several studies have looked at the economic burden of poor mental health in terms of labor market outcomes (Alexandre & French,  2001 ; Banerjee et al.,  2017 ; Chatterji et al.,  2007 , 2011 ; Frijters et al.,  2014 ; Hamilton et al.,  1997 ; Marcotte & Wilcox‐Gok,  2003 ; Peng et al.,  2016 ), and educational attainment (Currie & Stabile,  2006 ; Ding et al.,  2009 ; Eisenberg et al.,  2009 ; Fletcher,  2010 ; Fletcher & Wolfe,  2008 ). Yet, the healthcare costs associated with the diagnosis and treatment of mental disorders are the most significant direct economic cost (Trautmann et al.,  2016 ). 1 A few studies have examined such healthcare costs associated with depression, particularly among young adults, which show that depression is correlated with higher healthcare spending (Bodden et al.,  2018 ; Keenan‐Miller et al.,  2007 ; Lee et al.,  2017 ). Merely examining the association between mental disorders such as depression and medical costs can be problematic due to several reasons. First, there is a possibility of negative selection bias due to the socioeconomic gradient in mental health (Byles et al.,  2012 ; Hammarström et al.,  2011 ; Kosidou et al.,  2011 ). Specifically, individuals with mental illness are more likely to be from socioeconomically disadvantaged backgrounds with lower utilization of healthcare services, resulting in an underestimate of healthcare costs. Second, unobserved heterogeneity such as genetic disposition, level of health literacy, attitudes and preferences can be correlated with both mental health and healthcare use, leading to biased estimates (Roy & Schurer,  2013 ). Third, due to financial concerns, higher medical spending may in turn affect the mental health status of the individual, resulting in reverse causality or simultaneity bias (Hsieh & Qin,  2018 ). The prime aim of this study is to address these potential biases to quantify the effect of psychological distress in young women on publicly funded healthcare costs. In doing so, it contributes to the literature on healthcare consequences of mental health disorders in the following ways. First, to our knowledge, this study provides new evidence on the excess healthcare costs attributable to psychological distress in young women. We leverage a nationally representative panel of survey data linked to complete administrative records on healthcare costs from Australia's public health insurance system (Medicare). A key strength of this setting is that it minimizes bias due to misreporting of healthcare utilization and costs (Black et al.,  2018 ; Lebenbaum et al.,  2021 ), allowing us to derive precise and reliable estimates of excess healthcare costs of psychological distress. Second, we rely on a variety of econometric techniques to account for important sources of endogeneity bias. Our preferred empirical strategy is based on the classical two‐part model of healthcare costs with individual fixed‐effects to capture unobserved individual heterogeneity. We further complement our analysis by applying Oster ( 2019 ) method for selection on unobservables to address concerns of potential omitted variable bias. In addition, we also conduct several checks to examine the robustness of our estimates to sample attrition bias and measurement error. Third, in contrast to previous studies, we examine heterogeneous effects on several dimensions. The type of medical treatment differs with both the severity and chronicity of psychological distress (Druss & Rosenheck,  1999 ; Tomonaga et al.,  2013 ). Therefore, we first determine the healthcare costs attributable to different severity levels of psychological distress categorized as mild, moderate and severe. Next, we consider the varying effects of chronicity of psychological distress on healthcare costs. Following previous literature, we define chronicity as one‐time onset (reporting of symptoms only in one wave) and consistent onset (reporting of symptoms throughout the sampling frame) (Jones et al.,  2018 ; Pan et al.,  2020 ). Besides, we also conduct a separate analysis on monthly healthcare costs. Importantly, this allows us to provide new insights on the short and long term variations in healthcare costs following the occurrence of psychological distress. Our findings indicate that a one‐unit increase in K10 score (which represents an increase in the level of psychological distress) increases the conditional costs by 1.6%. Moreover, women with psychological distress (i.e., K10 score >24) have 15% higher annual healthcare costs, than women with no psychological distress. The additional annual cost of having moderate and severe psychological distress among women aged 18–27 years is about $43 million and $96 million, respectively. Additionally, we find that the effect of psychological distress on healthcare costs is highest during the first 6 months of onset, and gradually decreases afterwards. These findings are robust to several sensitivity checks. We support our findings by exploiting the richness of the administrative data on Medicare records. We show that the excess costs of psychological distress are driven by the use of mental health related services such as the use of psychologists, psychiatrists and prescribed antidepressants. We further show that women with psychological distress incur higher out‐of‐pocket costs on these mental health related services compared to non‐mental health specific services. Policy‐wise, the findings have significant implications. First, the excess healthcare cost of psychological distress is substantial. Second, individuals with psychological distress are more likely to develop major mental health disorders, which further aggravate the burden on healthcare resources. Therefore, our findings underscore the importance of policy interventions for early prevention and treatment of psychological distress to minimize not only the economic consequences of psychological distress, but also the larger costs of other mental illnesses. The remainder of the paper is organized as follows. In Section  2 we describe the data and the analysis sample. Section  3 outlines the methodology. The empirical results are presented in Section  4 , followed by robustness checks in Section  5 . Section  6 discusses the findings, and Section  7 concludes.

Coi Statement

The authors declare that they have no conflicts of interest.

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Mental Health Services National Health Programs Aged Australia Australia Female Health Care Costs Humans Longitudinal Studies Stress, Psychological Stress, Psychological Stress, Psychological Young Adult

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