VP62.36: Ureteral involvement in women with deep infiltrating endometriosis: preoperative risk factors

To evaluate clinical and sonographic preoperative risk factors for ureteral involvement in women with deep infiltrating endometriosis (DIE). We enrolled women with diagnosis of DIE scheduled for laparoscopic surgery. Transvaginal and transabdominal ultrasounds were performed to map endometriotic lesions, assessing longitudinal (length), anteroposterior (thickness) and transverse (width) diameters. Ureteral endometriosis (UE) was confirmed by laparoscopy and histology. To select risk factors we fit a multivariable fractional polynomial (MFP) regression model on a random training set of data. Among 300 women enrolled 145 (48.3%) had UE. In comparison with women without UE, women with UE had larger dimensions in all diameters of DIE nodule (longitudinal 2.5 ± 1.4cm vs. 3.2 ± 1.5cm p <0.001; anteroposterior 1.0 ± 0.5cm vs. 1.1 ± 0.5cm p 0.011; transverse 1.2 ± 0.7cm vs. 1.5 ± 0.7cm p <0.001) and hydronephrosis (0 vs. 16 p <0.001). Risk factors for UE were previous endometriosis surgery (adj OR = 3.87 p < 0.001), parametrial endometriosis (adj OR = 4.09 p < 0.001), adenomyosis (adj OR = 2.00 p 3cm was 2.49. Predicted probability of UE depending on different values of the transverse diameter is reported in figure 1. Preoperative risk factors associated with the likelihood of UE in women with posterior DIE were width of the nodule, hydronephrosis, previous endometriosis surgery, parametrial endometriosis and adenomyosis. Supporting information can be found in the online version of this abstract Supporting Information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.