緊急帝王切開時に診断した肝臓を出血源とするSHiPの一例

In: Journal of the Shizuoka Society of Obstetrics and Gynecology · 2026 · vol. 14(1) , pp. 44–50 · W7162621464
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AI-generated summary by claude@2026-06, 2026-06-12

This case report describes spontaneous hemoperitoneum in pregnancy originating from the liver, a rare condition with high mortality risk, and reviews relevant literature.

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AI-generated deep summary by claude@2026-06, 2026-06-12

The paper presents a case report of spontaneous hemoperitoneum in pregnancy (SHiP) in a 28-year-old woman managed for chronic hypertension, with evaluation driven by possible early HELLP syndrome based on rising blood pressure, recurrent vomiting, fetal growth restriction, a high sFlt-1/PlGF ratio, subtle liver enzyme elevation, and abnormal fetal monitoring, culminating in an emergency cesarean section. During surgery, hemoperitoneum was identified after peritoneal entry, but no pelvic source was found; intraoperative assessment by surgical consultation determined the bleeding to originate from the liver surface, and焼灼止血術 with topical hemostatic agents achieved hemostasis, with postoperative imaging showing a large hepatic hematoma without contrast leak. The authors note that preoperative diagnosis of SHiP is difficult and that their differential included HELLP-related hepatic subcapsular rupture, yet they concluded the intraoperative findings and atypical course supported SHiP. Relevance to endometriosis: the introduction and discussion cite endometriosis as a proposed risk factor/associated condition in SHiP and discuss Japanese data on typical bleeding sources, though this specific case involved liver surface bleeding without reported endometriosis history, so the paper relates to endometriosis as background context for SHiP rather than as the cause in this patient.

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Abstract

Spontaneous hemoperitoneum in pregnancy (SHiP) is defined as acute non-traumatic intraperitoneal bleeding during pregnancy. Although SHiP is extremely rare, with an incidence of approximately 1 in 10,000 deliveries, it has a higher risk of both perinatal and maternal mortality, as most cases are diagnosed after the patient has experienced significant blood loss. While the exact cause of SHiP remains unclear, it has been linked to conditions such as endometriosis and assisted reproductive technology. In Japan, the most common source of SHiP is reported to be the uterus and adnexa. In this study, we present a case of SHiP with liver surface bleeding, along with a brief review of relevant literature.

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endometriosis

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last seen: 2026-06-22T06:09:18.325942+00:00
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