Live birth after treatment of severe adenomyosis with a gonadotropin-releasing hormone agonist

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AI-generated summary by gemini-2.5-flash-lite, 2026-07-29

A woman with severe adenomyosis conceived and delivered a healthy baby shortly after stopping GnRH-agonist therapy, representing the first reported live birth following such treatment.

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Abstract

A patient with a 10-year history of secondary infertility underwent GnRH-a therapy with LA for 5 months to control symptoms of severe adenomyosis and to avoid an unwanted hysterectomy. Shortly after cessation of treatment, the patient conceived. A healthy male was delivered at term by cesarean section, which makes this the first report of a live birth after treatment of severe adenomyosis with a GnRH-a.

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Condition tags

endometriosisadenomyosisinfertility

MeSH descriptors

Endometriosis Leuprolide Pregnancy Outcome Uterine Diseases Adult Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Female Injections, Intramuscular Leuprolide Leuprolide Pregnancy Treatment Outcome Ultrasonography Uterine Diseases Uterine Diseases Uterus

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Cited by (1)

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Source provenance

europepmc
last seen: 2026-08-16T09:21:09.727480+00:00
pubmed
last seen: 2026-05-13T22:11:29.222973+00:00
unpaywall
last seen: 2026-08-16T06:22:10.609676+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine