Which SSRI is the best to give a young person with severe endometriosis for her depression and anxiety?

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The paper reviews fluoxetine and sertraline as widely used options for treating depression and anxiety in adolescents with severe endometriosis, noting the need for specialist consultation.

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This open publication addresses the clinical question of selecting the most appropriate selective serotonin reuptake inhibitor for adolescents suffering from severe endometriosis who also present with depression and anxiety. The text identifies fluoxetine and sertraline as widely reviewed therapeutic options for this specific demographic, emphasizing that treatment decisions require specialist consultation rather than independent prescription. No primary research data or comparative efficacy studies are presented within the document, which serves primarily as a descriptive overview of available pharmacological choices. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

Fluoxetine and sertraline are widely reviewed options for treating depression and anxiety in adolescents, including those with severe endometriosis, with a need for specialist consultation.
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Published July 31, 2025 | Version v1 Other Open Which SSRI is the best to give a young person with severe endometriosis for her depression and anxiety? Description Fluoxetine and sertraline are widely reviewed options for treating depression and anxiety in adolescents, including those with severe endometriosis, with a need for specialist consultation. Files 4a637a8e-def2-48b9-9e28-7b2e7bdf0c18.pdf Files (18.5 kB) | Name | Size | Download all | |---|---|---| | md5:dabfe658712ea6e7a4f76689e851b42b | 18.5 kB | Preview Download |

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endometriosis

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK