Outcome Measures and Adhesion Formation: Pain and Postsurgical Adhesion

In: Peritoneal Surgery · 2000 · pp. 321–327 · doi:10.1007/978-1-4612-1194-5_28 · W45540867
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This paper examines the evidence for a causal link between peritoneal adhesions and chronic abdominal/pelvic pain, and whether surgical adhesiolysis provides genuine relief.

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The paper/chapter considers whether peritoneal adhesions cause chronic abdominal and pelvic pain, reviewing evidence that adhesions—arising from causes including endometriosis, pelvic inflammatory disease, foreign materials, perforated appendix, or most commonly after intraabdominal surgery—are linked to infertility, bowel obstruction, and impaired intraperitoneal chemotherapy efficacy. It outlines the context that many surgeons and gynecologists perform laparotomy or laparoscopy with adhesiolysis for patients with suspected adhesions and chronic pain, with reported symptomatic improvement, while questioning whether this improvement reflects the surgery or a placebo effect. A key limitation is that the discussion emphasizes uncertainty and available evidence without presenting a new primary study, so causal attribution of adhesions to pain remains unresolved. Relevance to endometriosis: the paper explicitly mentions adhesions as occurring secondarily to endometriosis and situates this within the broader causes of adhesion formation in relation to chronic pelvic pain.

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Abstract

Adhesions within the peritoneal cavity may occur secondary to endometriosis, pelvic inflammatory disease, the presence of foreign material (such as sutures) or any other cause of pelvic inflammation such as perforated appendix, or, most commonly, following intraabdominal surgery. Adhesions are known to be associated with infertility,1 and acute bowel obstruction, and they can dele-teriously alter the efficacy of intraperitoneal chemotherapy. In addition, a major impact is their supposed association with chronic pain of the abdominal and pelvic cavities. Most surgeons and gynecologists no doubt have performed laparotomy or laparoscopy and adhesiolysis for patients with known or suspected adhesions and chronic pain, and indeed many of these patients may have had symptomatic improvement following their surgery. We are uncertain if this results from the surgery itself or is a placebo effect. The aim of this chapter is to consider the available evidence and to try to determine if adhesions do indeed cause pain. Preview Unable to display preview. Download preview PDF. Similar content being viewed by others

References

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