Endometriosis and estroprogestins: the chicken or the egg causality dilemma

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AI-generated summary by gemini-2.5-flash-lite, 2026-06-10

Endometriosis patients more frequently initiate estroprogestins for dysmenorrhea, potentially explaining a mild association with past oral contraceptive use.

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Abstract

Dysmenorrhea as a reason to initiate estroprogestins is significantly more common in women with endometriosis than in women without the disease. This might explain the previously reported mild association between endometriosis and past use of oral contraceptives.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Dysmenorrhea Endometriosis Ethinyl Estradiol Norpregnenes Adult Case-Control Studies Contraceptives, Oral Contraceptives, Oral Contraceptives, Oral Drug Combinations Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Ethinyl Estradiol Ethinyl Estradiol Female Humans Norpregnenes Norpregnenes

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Source provenance

europepmc
last seen: 2026-09-16T06:11:32.772430+00:00
pubmed
last seen: 2026-05-13T22:17:00.782903+00:00
unpaywall
last seen: 2026-09-16T06:28:21.314993+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine