Aging of the endometrium
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This paper reviews the structure and function of the endometrium, focusing on its two layers, the basalis and functionalis, and the reparative processes within the basalis.
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Abstract
The uterus has only one significant but extremely important function: the continuation of the species. The implantation of an embryo, the provision of a blood supply to the developing fetus, the formation of a mechanism for transmission of nutrients from the mother to the fetus, and resultant parturition all take place in the uterus. The uterus is composed of two distinctly different tissues – the endometrium and the myometrium. The endometrium consists of two discrete layers – the basalis and the functionalis. The functionalis is shed regularly through the necrosis and sloughing associated with menstruation.1 The basalis portion remains intact and is the site of the normal endometrial reparative process.2
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