Transvaginal Expulsion of a Fibroid After Transvaginal Radiofrequency Ablation: A Complication or a Benefit?

Cannone F, Francesco Cannone, Gianfranco Morreale, Morreale G, Billeci M, Ferdinando Antonio Gulino
Reports (MDPI) · 2026 · vol. 9(2) · doi:10.3390/reports9020145 · PMID:42200849 · PMC13214798
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A case report describes the transvaginal expulsion of a uterine fibroid following radiofrequency ablation, noting that this rare event may represent either a complication or a therapeutic outcome requiring careful clinical management.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-11 · read from full text ⓘ

This case report describes a patient who experienced the spontaneous transvaginal expulsion of a uterine fibroid following treatment with transvaginal radiofrequency ablation. The authors present this event as a potential complication or benefit, noting that the procedure successfully reduced the fibroid volume and led to its natural discharge through the vaginal canal without surgical intervention. The paper highlights the clinical course and management of this specific outcome in a single patient setting. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

Uterine fibroids are among the most common benign tumors affecting women, with a prevalence reaching up to 50-60% in those over 40 years of age, although often underestimated due to asymptomatic cases. Radiofrequency ablation (RFA) represents a minimally invasive alternative to surgery for selected patients. We report the case of a 41-year-old woman with symptomatic uterine fibroids (FIGO type 4, size of 5 cm) treated with transvaginal RFA. One month post- treatment, the fibroid showed partial volume reduction. Two months after the procedure, the patient presented with foul-smelling discharge and heavy bleeding. Ultrasound confirmed complete fibroid migration into the cervical canal. Vaginal removal was performed without complications. Fibroid expulsion after RFA is a rare event that may represent either a complication or a therapeutic outcome. A balanced interpretation and appropriate clinical management are required. Further studies are needed to clarify its clinical significance.
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Data

The original contributions presented in this work are included in the article. Further inquiries can be directed to the corresponding author.

Author

Conceptualization, M.B.; investigation, G.M.; resources, M.B.; data curation, F.A.G.; writing—original draft preparation, M.B.; writing—review and editing, F.C. All authors have read and agreed to the published version of the manuscript.

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This research received no external funding.

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Informed consent was obtained from all subjects involved in the study. Written informed consent has been obtained from the patient to publish this paper.

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The authors declare no conflicts of interest.

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Ethical review and approval were waived for this study; the ASP Siracusa Ethics Committee on Scientific Ethics waived the need for IRB approval for the case report, wherein the patient had signed informed consent.

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The original contributions presented in this work are included in the article. Further inquiries can be directed to the corresponding author.

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