Effect of caulis sargentodoxae prescription on the growth of endometrial cells cultured in vitro in rats

In: Tianjin Journal of Traditional Chinese Medicine · 2009 · W2348550120
Lab / animal OA: closed CC0 ⤵ 1 in-corpus citation
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Caulis Sargentodoxae prescription and Danazol significantly reduced rat endometrial cell viability in vitro in a time- and dose-dependent manner.

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Abstract

[Objective] To study the effect of Caulis Sargentodoxae prescription on the growth of endometrial cells cultured in vitro in rats. [Methods] Female Sprague-Dawley rats were collected to establish the model of endometriosis in vitro. After culture in media with different concentration Caulis Sargentodoxae prescription and Danazol drug-containing serum for 24, 48, 72 and 96 h, the cell viability was determined by MTT assay. [Results] After different culture periods in different concentration media with drug-containing rat serum, cell viability cultured with drug-containing serum was lower than control cells timeand dosadependently. [Conclusion] Caulis Sargentodoxae prescription and Danazol can restrain the growth of rat endometrial cells.

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endometriosis

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