Carcinosarcoma, endometrial intraepithelial carcinoma and endometriosis after tamoxifen therapy in breast cancer

Friedrich M; M Friedrich; Matthias G. Friedrich; C Villena-Heinsen; Villena-Heinsen C; D Mink; Mink D; Bonkhoff H; H Bonkhoff; Helmut Bonkhoff; Schmidt W; W Schmidt

doi:10.1016/s0301-2115(98)00166-3

Carcinosarcoma, endometrial intraepithelial carcinoma and endometriosis after tamoxifen therapy in breast cancer

Friedrich M, M Friedrich, Matthias G. Friedrich, C Villena-Heinsen, Villena-Heinsen C, D Mink, Mink D, Bonkhoff H, H Bonkhoff, Helmut Bonkhoff, Schmidt W, W Schmidt

European journal of obstetrics, gynecology, and reproductive biology · 1999 · vol. 82(1) , pp. 85–87 · doi:10.1016/s0301-2115(98)00166-3 · PMID:10192492 · W2126458530

article OA: closed CC0 ⤵ 3 in-corpus citations

View on OpenAlex View on PubMed View at publisher

⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This case report describes the occurrence of carcinosarcoma, endometrial intraepithelial carcinoma, and endometriosis in a breast cancer patient following tamoxifen therapy.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

The fourth case of heterologous mesodermal tumour of the uterine corpus, that developed, years following tamoxifen therapy for breast cancer in a postmenopausal woman with no previous pelvic irradiation, is presented with coincidental endometriosis and endometrial intraepithelial carcinoma. This coincidence after tamoxifen treatment appears to be an indication for the possible carcinogenic potency of tamoxifen.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Antineoplastic Agents, Hormonal Carcinoma in Situ Carcinosarcoma Endometriosis Mixed Tumor, Mullerian Tamoxifen Uterine Neoplasms Aged Antineoplastic Agents, Hormonal Breast Neoplasms Breast Neoplasms Breast Neoplasms Carcinoembryonic Antigen Carcinoma in Situ Carcinosarcoma Endometriosis Fatal Outcome Female Humans Mixed Tumor, Mullerian

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

Pathology of endometrium treated with tamoxifen. 1994

Cited by (3)

References (7)

Pathology of endometrium treated with tamoxifen. via openalex
W1995610950 via openalex
W1984501106 via openalex
W2154377786 via openalex
W2167916893 via openalex
W6649681816 via openalex
W2089182351 via openalex

Cited by (3)

Source provenance

europepmc: last seen: 2026-07-29T06:27:48.050232+00:00
openalex: last seen: 2026-06-04T00:00:01.174412+00:00
pubmed: last seen: 2026-05-13T22:10:29.640636+00:00

License: CC0 · commercial use OK

[1] Pathology of endometrium treated with tamoxifen. 1994