Malignant transformation of endometriosis in a cesarean section abdominal wall scar: a case report.

Erin E Stevens, Erin Stevens, Stevens EE, Tana S Pradhan, T. Pradhan, Pradhan TS, Yvonne Chak, Chak Y, Yi-Chun Lee, Lee YC
The Journal of reproductive medicine · 2013 · vol. 58(5-6) , pp. 264–6 · PMID:23763014 · W8009808
article OA: closed CC0 ⤵ 13 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-11 ⓘ

This case report describes a 51-year-old woman who developed malignant transformation of endometriosis within a cesarean section scar, treated successfully with neoadjuvant chemotherapy, debulking surgery, and radiotherapy.

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Abstract

BACKGROUND: Endometriosis occurring in a cesarean section abdominal wall scar is reported at a rate of 0.03-0.45%. Malignant transformation of this type of endometriosis is exceptionally rare. CASE: A 51-year-old, G3P2012, Black woman presented with a lump in her cesarean section abdominal wall scar that was increasing in size. Biopsy of the mass revealed metastatic adenocarcinoma with poorly differentiated, nonmucinous ovarian primary. She received 3 cycles of neoadjuvant chemotherapy and underwent an interval debulking with the final pathology showing malignant transformation of endometriosis within her abdominal wall scar. She then completed radiotherapy to the area and is disease-free 6 months later. CONCLUSION: Our combination of neoadjuvant chemotherapy and excision of the mass with negative margins followed by adjuvant radiotherapy is a feasible treatment option.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma, Clear Cell Carcinoma, Endometrioid Cell Transformation, Neoplastic Cesarean Section Cicatrix Endometriosis Abdominal Wall Abdominal Wall Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Adenocarcinoma, Clear Cell Carcinoma, Endometrioid Carcinoma, Endometrioid Carcinoma, Endometrioid Cell Transformation, Neoplastic Cesarean Section Cicatrix Endometriosis Female Humans

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (13)

Source provenance

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License: CC0 · commercial use OK