Path Analysis on The Associations between Stress, Polycistic Ovarium Syndrome, and the Risk of Infertility in Female of Reproductive Age

In: Strengthening Hospital Competitiveness to Improve Patient Satisfaction and Better Health Outcomes · 2019 · pp. 167 · doi:10.26911/the6thicph.03.25 · W4254380885
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Infertility among women was directly associated with age, BMI, endometriosis, myoma uterine, metabolic syndrome, PCOS, and employment, and indirectly associated with stress and lifestyle.

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This case-control study employed path analysis to identify factors associated with infertility risk in 200 women of reproductive age attending a hospital in Surakarta, Indonesia. The results indicated that infertility was directly and positively influenced by age over 35, elevated body mass index, metabolic syndrome, uterine myomas, polycystic ovary syndrome, and employment status. Additionally, high stress levels and lifestyle factors were found to indirectly affect the risk of infertility among the participants. Relevance to endometriosis: listed as one direct positive predictor of infertility alongside PCOS and myoma uterine, though the paper's main focus is on a broader path analysis of multiple causes rather than endometriosis specifically.

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Abstract

Background: Polycystic ovary syndrome (PCOS) is a disorder that associates with an imbalance in female sex hormones. It represents 80% of anovulatory infertility cases. The purpose of this study was to examine factors associated with the risk of infertility among female of reproductive age using path analysis model. Subjects and Method: A case control study was carried out in Dr. Moewardi hospital, Surakarta, from May to July 2019. A sample of 200 women was selected by fixed disease sample. The dependent variable was infertility. The independent variables were PCOS, body mass index (BMI), lifestyle, age, stress, metabolic syndrome, endometriosis, and myoma uterine. The data were obtained from medical record and questionnaire. The data were analyzed by path analysis run on Stata 13. Results: Infertility among women was directly and positively affected by age 35 years old (b= 2.20; 95%CI= 0.95 to 3.44; p= 0.001), BMI >25 (b= 2.11; 95%CI= 0.81 to 3.41; p= 0.001), endometriosis (b= 1.61; 95%CI= 0.16 to 3.06; p= 0.029), myoma uterine (b= 1.88; 95%CI= 0.56 to 3.20), metabolic syndrome (b= 2.73; 95%CI= 1.39 to 4.07; p <0.001), PCOS (b=4.76; 95%CI= 2.33 to 7.19; p<0.001), and employment (b= 2.11; 95%CI= 0.81 to 3.41; p= 0.001). It was indirectly affected by high stress and lifestyle. Conclusion: Infertility among women is directly and positively affected by age 35 years old, BMI >25, endometriosis, myoma uterine, metabolic syndrome, PCOS, and employment. It is indirectly affected by high stress and lifestyle.
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Abstract

Background: Polycystic ovary syndrome (PCOS) is a disorder that associate s with an imbalance in female sex hormones. It represents 80% of anovulatory infertility cases. The purpose of this s tudy was to examine factors associated with the risk of infertility among female of reproductive age using path analysis model. Subjects and Method : A case control study was carried out in Dr. Moewardi hos - pital, Surakarta, from May to July 2019. A sample of 200 women was selected by fixed disease sample. The dependent variable was infertility. The independent variables were PCOS, body mass index (BMI), lifestyle, age, stress, metabolic syndrome, endo metrio- sis, and myoma uterine. The data were obtained from medical record and ques tion- naire. The data were analyzed by path analysis run on Stata 13.

Results

Infertility among women was directly and positively affected by age ≥35 years old (b= 2.20; 95%CI= 0.95 to 3.44; p= 0.001), BMI >25 (b= 2.11; 95%CI= 0.81 to 3.41; p= 0.001), endometriosis (b= 1.61; 95%CI= 0.16 to 3.06; p= 0.029), myoma uterine (b= 1.88; 95%CI = 0.56 to 3.20), metabolic syndrome (b= 2.73; 95%CI = 1.39 to 4.07; p <0.001), PCOS (b=4.76; 95%CI = 2.33 to 7.19; p<0.001), and employment (b= 2.11; 95%CI= 0.81 to 3.41; p= 0.001). It was indirectly affected by high stress and lifestyle.

Conclusion

Infertility among women is directly and positively affected by age ≥35 years old , BMI >25, endometriosis, myoma uterine, metabolic syndrome, PCOS, and employment. It is indirectly affected by high stress and lifestyle.

Keywords

infertility, polycistic ovarium syndrome, path analysis Correspondence: Suci Arsita Sari . Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085786179994.

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endometriosisinfertility

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