Single-Cell and Spatial Transcriptomic Profiling Reveals Mechanisms of Angiogenesis and Fibrosis in Adenomyosis

Duan, Maoteng
2025 · doi:10.5281/zenodo.17078289 · W7080544883
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Abstract

This dataset originates from a multi-omics study of adenomyosis, a common gynecologic disorder characterized by limited therapeutic options and poorly understood molecular mechanisms. Using single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST), we generated a comprehensive cellular and spatial atlas of adenomyosis and further integrated publicly available bulk RNA-seq datasets for comparative analysis.
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Published September 8, 2025 | Version 1.0.0 Dataset Open Single-Cell and Spatial Transcriptomic Profiling Reveals Mechanisms of Angiogenesis and Fibrosis in Adenomyosis Authors/Creators Description This dataset originates from a multi-omics study of adenomyosis, a common gynecologic disorder characterized by limited therapeutic options and poorly understood molecular mechanisms. Using single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST), we generated a comprehensive cellular and spatial atlas of adenomyosis and further integrated publicly available bulk RNA-seq datasets for comparative analysis. Files Files (4.6 GB) | Name | Size | Download all | |---|---|---| | md5:8617f4f47324d88a19e558c58c7c4ae5 | 4.6 GB | Download |

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