Characterization of Nanocellulose Derived from Aloe Vera Using Two Distinct Nanofabrication Techniques

Abstract Introduction: Aloe vera has been extensively studied for its medicinal properties, including anti-inflammatory and antibacterial effects, and has been utilized in dentistry for several biomedical applications, including dentistry. Nanocellulose (NC), a natural fiber derived from cellulose, has been synthesized for several biomedical applications, including dentistry, where it has improved the mechanical properties of dental materials. This study aims to extract A. vera-based nanocellulose using two distinct nanofabrication methods, ultrasonication and cryocrushing, and characterize the resulting A. vera-derived nanocellulose, with potential applications in dentistry. Method After extracting the inner gel-like part of A. vera, the nanoization process was carried out utilizing two distinct nanofabrication techniques. After that to confirm the nanoization, transmission electron microscope (TEM) analysis and to determine the thermal stability and compare the effective materials, before and after using two distinct nanofabrication techniques, and simultaneous thermal analysis of STA and GC-MS was performed. Results The successful transformation of A. vera extract into A. vera-derived nanocellulose by both nanofabrication techniques without change in its chemical structure and thermal stability were confirmed based on TEM, GC-MS and STA analyses. Conclusion The successful nanoization of A. vera extract by both nanofabrication techniques were done.