Mapping of Digital Health Interventions to address latent Tuberculosis Infection: A Scoping Review protocol

Introduction: Globally, TB is one of the top 10 causes of mortality due to a single infectious agent “Mycobacterium Tuberculosis”, responsible for more than 10 million global infections each year and it is estimated that around 170 million people’s LTBI will develop active TB in future. Digital health interventions are gradually being integrated into TB care and are tested and evaluated in trials focused specifically on TB and very few on LTBI care. This review outlines the globally published literature on digital health interventions implemented to address LTBI and to describe various components of digital health interventions. Methods Arksey and O’Malley’s scoping review methodological framework will be followed to conduct this review. Searches will be conducted in five databases and hand search of references studies included. Two independent reviewers will be conducting title and abstract screening followed by full-text screening, data extraction, and quality appraisal. Results will be summarized to generate findings of the digital health interventions to address LTBI and reported in a tabular format and narrative synthesis conducted. Conclusion This review will be beneficial for synthesizing evidence of the role of digital health interventions, opportunities and challenges to address LTBI care and facilitate decision-making across diverse stakeholders such as clients, health care providers, health systems or resource managers, and data services. This scoping review will inform researchers, policy makers, and decision makers to design, develop and expand the use of an innovative and evidence based digital health technology intervention for improved LTBI care.