A Review of Transdiagnostic Mechanisms in Cognitive Behavior Therapy

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Abstract

Cognitive-behavior therapies (CBTs) are the gold-standard treatment for many psychiatric conditions. However, relatively little is known about how CBTs work. By characterizing these mechanisms, researchers can ensure CBTs retain their potency across diagnoses and delivery contexts. We review three classes of putative mechanisms: CBT-specific skills (e.g., cognitive restructuring, behavioral activation), transtheoretical mechanisms (e.g., therapeutic alliance, treatment expectancies, self-efficacy beliefs), and psychopathological mechanisms (aversive reactivity, positive affect, attachment style). We point to future research within each class and emphasize the need for more intensive longitudinal designs to capture how each class of mechanisms interacts with the others to improve outcomes.

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europepmc
last seen: 2026-05-20T01:45:00.602351+00:00