Therapeutic Choices for Ovulatory Dysfunctional Abnormal Uterine Bleeding: A Cross-sectional Study in Chinese Women

Background: Ovulatory dysfunction is the primary cause of abnormal uterine bleeding (AUB); however, data on nationwide therapeutic choices of Chinese women are lacking. The aim of this study was to investigate the therapeutic choices of ovulatory dysfunctional abnormal uterine bleeding (AUB-O) in Chinese women and analyse the factors on the selection results. Methods: This was a cross-sectional study involving 3527 patients with AUB-O diagnosed by local doctor between 14 and 55 years old. We used questionnaire compiled according to the Chinese AUB-O treatment guidelines to collect the demographic and therapeutic information. Their therapeutic choices were regarded as generally representative of the nation ’s choices. Results: The patients were divided into the juvenile group (14–18 years old, n = 84), the reproductive group (19–39 years old, n = 2962) and the senior group (perimenopausal period: 40–55 years old, n = 481). The results showed that irregular menstruation (37.6% − 46.3%), dysmenorrhea (29.9% − 44.4%), and heavy menstrual bleeding (16.7% − 32.2%) were the main symptoms in Chinese AUB-O patients of different ages. Most of the patients chose to seek help in the Department of General Gynecology (78.6% − 90.7%). Among the therapeutic options, combined oral contraceptives (COCs), such as Yasmin I and Yasmin II, met the treatment expectations with high acceptance among patients (36.6%-52.2%). Conclusions: It is important to strengthen the endocrine diagnosis ability of doctors in the Department of General Gynecology. With rational education and clinical applications, COCs are expected to become a more prevalent therapeutic option for AUB-O.