The Effect of Abdominal Radical Trachelectomy on Ovarian Reserve: Serial Changes in Serum Anti-Müllerian Hormone Levels
article
OA: gold
CC0
Abstract
AIM: To evaluate the effect of abdominal radical trachelectomy on ovarian reserve and compare it with abdominal radical hysterectomy and a control group that did not have surgery. METHOD: We enrolled eighteen women who had abdominal radical trachelectomy with pelvic lymphadenectomy and sixteen patients who had abdominal radical hysterectomy for this study. Ten thousand one hundred eighty-six women were also included as a control group for comparison. The Mann-Whitney U test was used for comparison of patient characteristics and comparison of serum anti-Müllerian hormone levels between the three groups. RESULTS: Serum anti-Müllerian hormone levels in patients with abdominal radical trachelectomy were significantly higher than those of patients with abdominal radical hysterectomy (P<0.05). Serum anti-Müllerian hormone levels in the abdominal radical hysterectomy group were significantly lower than those in the control group (P=0.02), with no significant difference between the abdominal radical trachelectomy and control groups. These data indicated that abdominal radical trachelectomy did not affect ovarian function with respect to ovarian reserve and the response to ovarian stimulation. CONCLUSIONS: Serum anti-Müllerian hormone levels could be useful as a marker of ovarian reserve after abdominal radical trachelectomy. It is important to avoid postoperative complications causing a reduction in ovarian function to accomplish fertility-sparing surgery.
My notes (saved in your browser only)
Citation neighborhood (sparse)
Too few in-corpus citations on either side for a chart; here are the lists.
Cites (1)
References (24)
- The post-operative decline in serum anti-Mullerian hormone correlates with the bilaterality and severity of endometriosis via openalex
- doi:10.1111/j.1471-0528.2004.00452.x via openalex
- doi:10.1002/(sici)1097-0142(20000415)88:8<1877::aid-cncr17>3.0.co;2-w via openalex
- doi:10.1093/humrep/del421 via openalex
- doi:10.1016/0092-8674(86)90783-x via openalex
- doi:10.1093/humrep/deg043 via openalex
- doi:10.1016/j.ygyno.2010.12.345 via openalex
- doi:10.1111/j.1479-828x.2005.00332.x via openalex
- doi:10.1016/j.mce.2004.09.008 via openalex
- doi:10.1093/humrep/deh718 via openalex
- doi:10.1093/humrep/deg042 via openalex
- doi:10.1093/jncimonographs/lgi026 via openalex
- doi:10.1093/humrep/dem204 via openalex
- doi:10.1016/j.ygyno.2004.07.060 via openalex
- doi:10.1016/j.ygyno.2009.06.036 via openalex
- doi:10.1016/j.ygyno.2010.12.072 via openalex
- doi:10.1093/humrep/dei203 via openalex
- doi:10.1016/j.fertnstert.2005.09.019 via openalex
- doi:10.1093/humrep/17.12.3065 via openalex
- doi:10.1016/j.fertnstert.2004.03.061 via openalex
- doi:10.1093/molehr/gah015 via openalex
- doi:10.1016/j.ygyno.2010.01.039 via openalex
- doi:10.1016/s0015-0282(01)03201-0 via openalex
- doi:10.1016/s1470-2045(10)70084-x via openalex
SciLite annotations
chemicals 2
peptide
positron
organisms 1
noordeloos 2009062
Source provenance
- europepmc
- last seen: 2026-06-20T06:14:18.781669+00:00
- openalex
- last seen: 2026-05-11T06:35:44.859312+00:00
- scilite
- last seen: 2026-05-18T04:26:01.642840+00:00
License: CC0
· commercial use OK