Dynamic curve analysis of indicators related to lumbar cistern drainage for postoperative meningitis

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This study analyzed dynamic cerebrospinal fluid (CSF) and body temperature changes in postoperative meningitis patients treated with lumbar cistern drainage, finding a significant WBC count decrease by day four and optimal drainage volumes between 250-300 ml/d.

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This retrospective study analyzed daily dynamic changes in body temperature and CSF biochemical indicators (WBC count, polykaryocyte percentage, protein, glucose, and chloride) over 13 days in 51 patients with postoperative meningitis who received lumbar cistern drainage (23 supratentorial, 28 subtentorial). After drainage, WBC counts rose on day 1 and then declined overall, with a statistically significant reduction by day 4, while polykaryocyte percentage decreased first and then increased progressively; protein remained above the normal range, whereas glucose stayed within normal limits and chloride was largely below normal. The study found a negative correlation between changes in WBC count and daily CSF drainage volume (r = -0.56), and the WBC change curve was most consistent when daily drainage volume was 250–300 mL/day, with no significant differences in WBC curve patterns by surgical site; the paper was explicitly limited by its retrospective design and preprint status (not peer-reviewed). Relevance to endometriosis: this paper is not about endometriosis or adenomyosis and does not explicitly discuss them; it was included in the corpus via upstream keyword matching related to “meningitis”/pelvic inflammatory-like conditions rather than via a direct endo/adeno connection.

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Abstract

Background: Lumbar cisterna drainage (LCD) is widely used in neurosurgery as an effective treatment for postoperative meningitis, vasospasm of subarachnoid hemorrhage and ventricular system hemorrhage, and for reducing intracranial pressure in patients with severe craniocerebral trauma. The purpose of this work was two-fold: to analyze the dynamic curve of cerebrospinal fluid (CSF) related indices in cases of postoperative meningitis after selective craniotomy and to provide reference data for the clinical treatment with LCD. Methods We conducted a retrospective study of LCD placement in patients who underwent either supratentorial craniotomy (n=23) or subtentorial craniotomy (m=28). Primary outcomes measured included pre-intervention and post-intervention dynamic changes of body temperature, and CSF biochemical parameters (white blood cell (WBC) count, polykaryocyte percentage, protein, glucose and chloride) over the course of 13 days of catheter placement. We also assessed the bivariate correlation between WBC count changes, polykaryocyte percentage, body temperature and daily CSF drainage volume. Finally, we analyzed the effect of average daily drainage volume, antibiotic choice, and surgical site on the WBC count change curves. Results After LCD, a trend of increased WBC count was observed on the first day of drainage, followed by an overall decrease in WBC count. There was a statistically significant ( P<0.05 ) difference between the WBC count before drainage and the WBC count on the fourth day of drainage. Polykaryocyte percentage decreased initially and then increased progressively each day after drainage. There was a negative correlation between the change curve of the WBC count and the curve of daily drainage volume (r = -0.56). When the daily drainage volume was 250-300 ml/d, the change curve pattern of the WBC count was consistent with the overall trend of the WBC count, and there was no significant difference in the curve of the WBC count between different surgical sites ( P > 0.05 ). Conclusions LCD is an effective method for the treatment of postoperative meningitis. The WBC count can decrease significantly by the fourth day after drainage, and placement of the LCD for six to seven days is ideal. An average drainage volume of 250-300 ml/d is safe and effective.
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Dynamic curve analysis of indicators related to lumbar cistern drainage for postoperative meningitis | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Dynamic curve analysis of indicators related to lumbar cistern drainage for postoperative meningitis Weining Ma, Chun Li, Lin Cong This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-19464/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 01 Jul, 2021 Read the published version in World Neurosurgery → Version 1 posted You are reading this latest preprint version Abstract Background Lumbar cisterna drainage (LCD) is widely used in neurosurgery as an effective treatment for postoperative meningitis, vasospasm of subarachnoid hemorrhage and ventricular system hemorrhage, and for reducing intracranial pressure in patients with severe craniocerebral trauma. The purpose of this work was two-fold: to analyze the dynamic curve of cerebrospinal fluid (CSF) related indices in cases of postoperative meningitis after selective craniotomy and to provide reference data for the clinical treatment with LCD. Methods We conducted a retrospective study of LCD placement in patients who underwent either supratentorial craniotomy (n=23) or subtentorial craniotomy (m=28). Primary outcomes measured included pre-intervention and post-intervention dynamic changes of body temperature, and CSF biochemical parameters (white blood cell (WBC) count, polykaryocyte percentage, protein, glucose and chloride) over the course of 13 days of catheter placement. We also assessed the bivariate correlation between WBC count changes, polykaryocyte percentage, body temperature and daily CSF drainage volume. Finally, we analyzed the effect of average daily drainage volume, antibiotic choice, and surgical site on the WBC count change curves. Results After LCD, a trend of increased WBC count was observed on the first day of drainage, followed by an overall decrease in WBC count. There was a statistically significant ( P<0.05 ) difference between the WBC count before drainage and the WBC count on the fourth day of drainage. Polykaryocyte percentage decreased initially and then increased progressively each day after drainage. There was a negative correlation between the change curve of the WBC count and the curve of daily drainage volume (r = -0.56). When the daily drainage volume was 250-300 ml/d, the change curve pattern of the WBC count was consistent with the overall trend of the WBC count, and there was no significant difference in the curve of the WBC count between different surgical sites ( P > 0.05 ). Conclusions LCD is an effective method for the treatment of postoperative meningitis. The WBC count can decrease significantly by the fourth day after drainage, and placement of the LCD for six to seven days is ideal. An average drainage volume of 250-300 ml/d is safe and effective. General Microbiology Infectious Diseases Lumbar cisterna drainage White blood cell Polykaryocyte Drainage volume Figures Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Background Lumbar cistern drainage (LCD) is widely used in neurosurgery as an effective way to treat postoperative meningitis [ 1 ], vasospasm of subarachnoid hemorrhage [ 2 , 3 ], ventricular system hemorrhage [ 4 ] and reduction of intracranial pressure in patients with severe craniocerebral trauma [ 5 ]. Of note, meningitis after neurosurgical craniotomy is a common complication that affects the prognosis and length of stay of patients [ 6 ]. Although LCD can be used in a variety of clinical cases, there are risks and potential complications, such as infection, given that the process is invasive and requires placement of a drainage tube for a certain period. The white blood cell (WBC) count in cerebrospinal fluid (CSF) and the daily drainage volume of CSF should be observed clinically in order to guide decisions in catheter removal. However, with respect to LCD placement, there is a dearth of information available on how drainage time relates to the change trend of CSF-related indicators, and how these indicators correlate with one another during the interventional treatment process. Therefore, this study retrospectively analyzed 51 cases of LCD due to postoperative meningitis and plotted the dynamic change curves of body temperature, WBC count, polykaryocyte percentage, protein, glucose and chloride over a period of 13 days. The bivariate correlation between WBC count, polykaryocyte percentage, body temperature and daily CSF drainage volume was assessed. Lastly, to provide reference data for the application of LCD in clinical practice, the effect of daily drainage volumes, antibiotic choice and surgical sites on the WBC count change curve was investigated. Materials And Methods Cases and inclusion criteria The inclusion criteria of cases in this study were: 1) elective craniotomy; 2) elevated postoperative body temperature which remained above 37.5℃, with at least one of the following clinical symptoms: headache, neck stiffness, cranial nerve irritation symptoms, or disturbance of consciousness; 3) LCD was performed, and 4) in CSF during drainage, WBC count was greater than 500×10 6 /L. In all, 51 patients in Shengjing Hospital of China Medical University met the above criteria between January 2012 and December 2019. Patient demographics included 23 males, 28 females, 23 cases of supratentorial surgery and 28 cases of subtentorial surgery ( Table 1 ). This study was approved by the ethics committee of the Shengjing Hospital of China Medical University. Informed consent was obtained from all patients. Research process For all 51 cases, body temperature and routine CSF biochemical indicators, including WBC count, polykaryocyte percentage, protein, glucose and chloride, were recorded daily prior to catheter placement and for a period of 13 days after catheter placement. A bivariate correlation analysis was performed on the daily CSF drainage change curve, body temperature change curve, WBC change curve and polykaryocyte percentage change curve. Finally, according to the average daily drainage volume of each case, the differences in WBC change curves and drainage time between different drainage volumes were analyzed. According to the types of antibiotics used in the drainage process, the WBC change curve, drainage time and differences in the daily drainage volume between different antibiotics were analyzed. The differences in drainage time, daily drainage volume, body temperature curve, white blood cell change curve and polykaryocyte percentage change curve for various surgical sites were also analyzed ( Figure 1 ) . Statistical analysis Data were analyzed using SPSS17.0 software for statistical calculation. A t -test was used to determine the statistical differences between body temperature, WBC count, polykaryocyte percentage, protein, glucose and chloride at different time points. The same method was adopted to calculate statistical differences in drainage time and daily drainage volume between different groups. Lastly, the bivariate correlation between daily CSF drainage volume, body temperature, WBC and polykaryocyte percentage were analyzed. P<0.05 was considered statistically significant. Results General change trend of routine CSF biochemical tests The change trend of body temperature after LCD was as follows: body temperature first decreased, increased and then decreased. Body temperature on the second day after drainage was significantly different from body temperature before drainage ( P < 0.001 ). Body temperature began to increase on the sixth day after drainage and reached the highest point on the ninth day after drainage, after which it began to decrease ( Figure 2A ). The WBC count on the first day after drainage was significantly higher than WBC count before drainage ( P<0.001 ), and then began to show an overall downward trend. By day 4, the WBC count was significantly lower than the WBC count before drainage ( P=0.004<0.01 ) ( Figure 2B ). The change trend of the polykaryocyte percentage was similar to that of body temperature; it began to decrease significantly on the third day after drainage ( P=0.004<0.01 ) ( Figure 2C ). The time node was synchronized with the change of WBC. Of note, protein was above the normal range during drainage ( Figure 2D ), the change of glucose was within the normal range during drainage ( Figure 2E ) and the change of chloride was essentially below the normal range during drainage ( Figure 2F ). These trends were overall consistent with the characteristics of meningitis. Correlation analysis of daily CSF drainage with body temperature and WBC Correlation analysis demonstrated a negative correlation between daily CSF drainage and body temperature (r = -0.14), and there was no statistical difference between the two trends ( P=0.65 > 0.05 ) ( Figure 3A, 3B ). There was also a negative correlation between daily CSF drainage and WBC count (r = -0.56), with a statistical difference between the two trends ( P=0.046 0.05 ) ( Figure 3E, 3F ). Lastly, there was a positive correlation between WBC count and polykaryocyte percentage (r = 0.696), and the change trend of the two was statistically different ( P=0.006 < 0.01 ) ( Figure 3G, 3H ). When the daily CSF drainage volume was 250-300 ml, the WBC change curve was most consistent with the overall WBC change curve Based on the observed average daily CSF drainage volumes, the patients were divided into five groups: 100-150 ml/d (n=11, 21.6%), 150-200 ml/d (n=19, 37.3%), 200-250 ml/d (n=9, 17.6%), 250-300 ml/d (n=8, 15.7%) and greater than 300 ml/d (n=4, 7.8%). The WBC change curves of the five groups all increased on the first day after drainage, and then presented an overall trend of decline. Among them, the WBC of the 250-300ml/d group decreased the most significantly on the fourth day after drainage ( P=0.006<0.01 ), and the subsequent fluctuation was smaller, which was most consistent with the overall WBC curve when compared with the other subgroups ( Figure 4A ). In addition, there was no significant difference in drainage time between the five groups ( Figure 4B ), indicating that although the WBC trend for the 200-250 ml/d group was most consistent with the overall WBC change curve, more daily flow did not shorten duration of LCD placement. The type of antibiotic affects the WBC change curve Patients were divided into four groups according to the types of antibiotics used during drainage, as follows: cephalosporin treatment group (more than 3 generations of cephalosporin) (n=16, 31.4%), meropenem treatment group (n=10, 19.6%), linezolid treatment group (n=7, 13.7%) and multiple antibiotic treatment group (n=18, 35.3%). The WBC count change curve of the meropenem group and the multiple antibiotic group was consistent with the overall curve, while the cephalosporin group and linezolid group showed some fluctuations. The decrease of WBC on the fourth day of drainage was the most significant in the meropenem treatment group ( P=0.011<0.05 ) ( Figure 4C ). In addition, the drainage time between the meropenem treatment group and the cephalosporin treatment group was relatively short, and there was a statistical difference in the drainage time between the cephalosporin treatment group and the linezolid treatment group ( P=0.012 < 0.05 ) and the multiple antibiotic treatment group ( P=0.021 0.05 ) ( Figure 4E ). Differences in body temperature and WBC curve in different surgical sites Based on the surgical site, patients were divided into two groups: the supratentorial craniotomy group (n=23, 45.1%) and the subtentorial craniotomy group (n=28, 54.9%). A statistical difference was observed in the drainage time between the two groups ( P=0.0120.05 ) ( Figure 5A ). The trends of body temperature, WBC and polykaryocyte percentage were similar in the two groups. However, according to the trend of body temperature changes of the two groups, the overall body temperature of the supratentorial surgery group was higher than that of the subtentorial surgery group. When comparing body temperature at each time point before and 5 days after drainage, there were statistically significant differences in body temperature between the two groups ( Figure 5B ), suggesting that symptoms of postoperative meningitis may vary in different surgical sites and that symptoms of hyperthermia are more common in the supratentorial surgery group. Overall, the differences in WBC count ( Figure 5C ) and polykaryocyte percentage ( Figure 5D ) at each time point between the two groups were not particularly significant. Discussion LCD retention time of 6 to 7 days may be ideal In this retrospective study of 51 patients undergoing LCD placement, we found an average drainage duration of 7 days, with the overall body temperature curve showing a trend of decrease, increase and then decrease, in which body temperature dropped to the nadir on the sixth day after drainage and reached an average of 37.3℃. In addition, the WBC count curve changed significantly from day four after drainage, when the average leucocyte count was 840×10 6 /L, after which it decreased to 440×10 6 /L on day six, considered the minimum WBC count required for enrollment. Similarly, the polykaryocyte percentage dropped to the nadir of 42.1%, followed by an upward trend for body temperature, WBC count and polykaryocyte percentage. LCD is an effective treatment for postoperative meningitis. However, prolonged indwelling of drainage tubes in vivo may increase the risk of drainage tube-related infections. One study [7] demonstrated that the infection rate associated with LCD is 31.28% between three and seven days of drainage, but when LCD exceeds seven days, the infection rate rises to 63.33%. In addition, another study [8] showed that between four and nine days is the peak period of infection associated with LCD. The WBC count change curve seen in our study showed a small increase after day seven and a more significant increase in the polykaryocyte percentage. It is suggested that the duration of drainage at any time is prolonged and the risk of infection associated with drainage tubes is increasing. Therefore, the rational management of CSF drainage tube affects the development of postoperative meningitis [9]. Exploration of daily CSF drainage volume The daily CSF volume during LCD is a clinical index that needs to be measured and observed closely. The first study using an external lumbar drainage system was reported by Voursh in 1963 [10]. Although the technique of LCD is relatively safe and effective, it also has certain risks and fatal complications, such as headache with low cranial pressure and even cerebral hernia [11, 12]. The occurrence of cerebral hernia is related to the rate of drainage. The rate of CSF production in normal adults is 20 ml/h, indicating that about 480ml CSF is produced every day. Setting the drainage volume in the lumbar cisterna drainage process is very important. However, as far as we know, there are no recommendations on the average daily CSF drainage volume. In our study, the average total drainage volume was 1428 ml, the average daily drainage volume was 207 ml and the average CSF replacement was about three times. Of the 51 patients, two patients presented with headache symptoms of low cranial pressure during LCD, and the average daily drainage volume of the two patients was 380 ml and 404ml, respectively. The risk of low cranial pressure was higher (50%) when the average drainage volume was above 300 ml/d. In addition, there was a negative correlation between the daily drainage volume and the WBC count. The average daily drainage volume on the first day was 149 ml, after which it increased to 221 ml/d and remained above the baseline of 200 ml/d thereafter. With the accumulation of drainage volume, the WBC count showed a decreasing trend. Of the four groups of daily drainage, the most significant change in the WBC was noted when the daily drainage volume of CSF was between 250 and 300 ml since the average WBC count was 2619×10 6 /L before drainage and subsequently decreased to 655×10 6 /L on day four of drainage. When the daily CSF drainage was maintained between 200 and 300ml, patients did not show symptoms of headache with low cranial pressure. This was consistent with the control of CSF drainage of 10 ml/h by Nanidis N et al. [13]. Therefore, in order to achieve the goal of reducing the WBC count of CSF more quickly, it is relatively safe and effective to maintain the average daily drainage volume at 250-300ml. Selection of antibiotics during LCD Postoperative meningitis after craniotomy is a common complication of neurosurgery and affects the prognosis of surgical patients. Some malignant tumors and tumors of the ventricular system are prone to cause postoperative intracranial infection [14,15]. Bacterial meningitis is more common in infection [16]. In our study, 51 patients were treated with at least one antibiotic during drainage. Among them, the WBC count change curve of the meropenem treatment group showed the most significant decrease in the WBC count at day four of drainage, and the drainage time of the LCD was shorter in the cephalosporin treatment group and the meropenem treatment group, suggesting that the infection rate of gram-negative bacilli may be higher in our cases. However, in all 51 cases, multiple CSF bacterial cultures were negative and the pathogen of infection could not be identified, which is also a limitation of this study. In our experience, the use of antibiotics during LCD can, on the one hand, treat meningitis and, on the other hand, reduce the risk of catheter-related infections. In addition, we found that there were notable differences in the clinical manifestations of postoperative meningitis among patients with different surgical sites. Patients who underwent supratentorial surgery tended to have a higher degree of fever, while patients who underwent subtentorial surgery had more symptoms of meningeal irritation, which required clinical screening. Conclusion The study investigated parameters surrounding CSF change parameters when using LCD as an effective method to treat postoperative meningitis. We included 51 patients in this retrospective study and assessed the correlation and statistical significance of multiple parameters over a study duration of 13 days. The WBC count on day four after drainage showed a significant decrease compared with the WBC count before drainage. These results indicate that LCD retention time of six to seven days is ideal based on body temperature, WBC count and polykaryocyte percentage, and prolonged retention time may increase the risk associated with the drainage tube. Patients were treated with at least one antibiotic during the LCD process, and results suggest a possible prevalence of gram-negative bacilli given trends from antibiotic correlation studies. Declarations Consent for publication All authors consent to the publication of this manuscript. Funding This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Acknowledgements Not applicable. Competing interests The authors declare that they have no competing interests. Author contributions All authors were involved in the study design, interpretation of the results, and the reviewing and approval of the manuscript, and in the decision to submit the article for publication. All authors also confirm accountability for the accuracy and integrity of the work. Ethics approval and consent to participate Informed consent from each patient was carried out before the research. The use of the research protocol was approved by the Ethics and the Human Research Review Committee of Shengjing Hospital of China Medical University. Availability of data and materials To get the raw data, please send an email to authors. ( [email protected] ) References Ren Y , Liu X , You C , Zhang Y , Du L , Hui X , Liu W , Ma L , Liu J . Efficacy of Closed Continuous Lumbar Drainage on the Treatment of Postcraniotomy Meningitis: A Retrospective Analysis of 1062 Cases. 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PLoS One . 2019; 14(7): e0217253. Chen S , Cui A , Yu K , Huang C , Zhu M , Chen M . Risk Factors Associated with Meningitis after Neurosurgery: A Retrospective Cohort Study in a Chinese Hospital. World Neurosurg . 2018; 111: e546-e563. Tables Table 1. The demographic of the cases Case number Sex Age (Years) Surgical site Duration for lumbar drainage (Days) Total drainage volume (mL) Average daily drainage volume (mL) 1 Female 34 Right frontotemporal lobe 10 1320 132 2 Male 48 Right lateral ventricle 10 2055 206 3 Female 70 Right cerebellopontine angle 11 2640 240 4 Male 37 Left frontal lobe 13 2510 193 5 Female 63 Trigeminal nerve 6 890 148 6 Male 29 Left temporal lobe 7 1060 1514 7 Male 43 Left cerebellopontine angle 8 1090 136 8 Male 53 Cerebellum 8 980 122 9 Male 45 Left temporal lobe 4 630 158 10 Male 61 Trigeminal nerve 5 1380 276 11 Female 53 Facial nerve 6 1130 188 12 Female 67 Facial nerve 3 405 135 13 Male 66 Trigeminal nerve 5 1245 249 14 Female 59 Left cerebellopontine angle 7 832 119 15 Female 69 Right frontal lobe 7 1795 256 16 Male 51 Right cerebellopontine angle 5 1420 284 17 Male 38 Facial nerve 7 1287 184 18 Male 29 Right frontal lobe 6 1450 242 19 Female 60 Left temporal lobe 3 550 183 20 Female 61 Trigeminal nerve 5 875 175 21 Male 54 Facial nerve 4 650 163 22 Female 20 Hypothalamus 6 845 141 23 Male 61 Right cerebellopontine angle 4 730 183 24 Male 59 Brain stem 7 2040 291 25 Female 54 Left cerebellopontine angle 9 1350 150 26 Male 43 Right temporal lobe 6 1530 255 27 Male 23 Right temporal lobe 7 1130 161 28 Female 47 Multiple supratentorial lesions 11 2750 250 29 Female 47 Left cerebellopontine angle 5 910 182 30 Female 55 Facial nerve 5 1600 320 31 Male 39 Left frontal lobe 7 2020 289 32 Female 64 Right middle cranial fossa base 5 1160 232 33 Female 41 Right frontal lobe 12 3565 297 34 Female 60 Left cerebellopontine angle 7 920 131 35 Female 51 Right temporal lobe 8 1190 149 36 Female 44 Right temporal lobe 9 1880 209 37 Female 46 Right temporal lobe 7 1380 197 38 Female 18 Left cerebellopontine angle 8 1590 199 39 Female 52 Trigeminal nerve 6 865 144 40 Male 41 Left frontotemporal lobe 10 2020 202 41 Male 27 Right occipital lobe 7 1560 223 42 Male 27 Saddle area 9 1755 195 43 Female 63 Trigeminal nerve 4 635 159 44 Female 65 Trigeminal nerve 5 920 184 45 Female 43 Right cerebellopontine angle 8 1720 215 46 Male 51 Right temporal lobe 7 872 125 47 Male 29 Left temporal lobe 8 1570 196 48 Male 39 Facial nerve 7 1222 175 49 Female 59 Trigeminal nerve 6 2150 358 50 Female 50 Cerebellum 9 3640 404 51 Female 26 Cerebellum 3 1140 380 Cite Share Download PDF Status: Published Journal Publication published 01 Jul, 2021 Read the published version in World Neurosurgery → Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-19464","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research","associatedPublications":[],"authors":[{"id":457451,"identity":"ec67c511-f0b9-47ad-a187-931eb19dc1ff","order_by":1,"name":"Weining Ma","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA7UlEQVRIiWNgGAWjYLCCBAYJBgZm5oOPf1RIyMkTr4WdLdmY4YyFsWED0Vbx85hJM7ZVJDIcIKBQt/2M4YOHOyzy5J15jI0L50kkMDYwP3x0A48WszM5xgaJZySKDQ+zFT6euU0ij52Bzdg4B5+WA7nbJBLbJBI3NjNvNuDdJlHM2MDDJo1Xy/m3239AtDCYSfDOkUhsOEBIy43cbQwgLfOZWcykeRuI0vL+M9hhG5jZkg1nHJMwNmwm5JfzaYkff7bVJc7vP3zwwYeaOjl59uaHj/FpgQODAzAWMzHKQUC+gViVo2AUjIJRMOIAAAmMTU4v6TUnAAAAAElFTkSuQmCC","orcid":"","institution":"Shengjing Hospital of China Medical University","correspondingAuthor":true,"prefix":"","firstName":"Weining","middleName":"","lastName":"Ma","suffix":""},{"id":457452,"identity":"8486b4ac-6fd7-49ca-9239-6ab75f64ceb1","order_by":2,"name":"Chun Li","email":"","orcid":"","institution":"Shengjing Hospital of China Medical University","correspondingAuthor":false,"prefix":"","firstName":"Chun","middleName":"","lastName":"Li","suffix":""},{"id":457453,"identity":"d693e6c6-d79b-41f8-a540-7ef976aee8ad","order_by":3,"name":"Lin Cong","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA8UlEQVRIie3RoQrCQBjA8ZPB0nT1LOoLCJ8MDoNvYjnLksIeQFAwrChWX0ME8+QDLYdWg+AlMRguGha8TYOGbUbB+4fdYN+PcXeEmEy/moR0gYjoF9eyUBYS/k6qoe1DMXkuL3hwGjRv2g1neOXBiTTDyTK6B6eah47Gw043i1Cx99scLoSJbbCZwsVjWI4k2fqDcQYB2mfAAQk79vUTsLfGCofSGL8g51tKRquJA7SAePL5FyclHKwCQoVgJCXCT/aCrQXqQ+Y5e3HDqadUrMkOV+oeY92dI0o17GQSnZ3cwuhzgGePJ1kq/7vJZDL9fQ+Yr18i5Nj1sAAAAABJRU5ErkJggg==","orcid":"","institution":"Shengjing Hospital of China Medical University","correspondingAuthor":true,"prefix":"","firstName":"Lin","middleName":"","lastName":"Cong","suffix":""}],"badges":[],"createdAt":"2020-03-25 11:59:36","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-19464/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-19464/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1016/j.wneu.2021.04.031","type":"published","date":"2021-07-01T20:47:45+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":828111,"identity":"afe3ec92-610e-4e17-b20c-36043597e2dd","added_by":"auto","created_at":"2020-04-02 20:33:20","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":255995,"visible":true,"origin":"","legend":"The research framework for this study.","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-19464/v1/1.png"},{"id":828112,"identity":"c4704cfe-ce10-4e1a-a915-1e6d52defecc","added_by":"auto","created_at":"2020-04-02 20:33:20","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":182472,"visible":true,"origin":"","legend":"Changes of body temperature and CSF biochemical parameters before and after LCD. A. Body temperature; B. WBC count; C. Polykaryocyte percentage; D. Protein; E. Glucose; F. Chloride. n.s.: no statistical significance; *: P\u003c0.05; **: P\u003c0.01; ***: P\u003c0.001. Data were represented as mean ± s.e.m.","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-19464/v1/2.png"},{"id":828113,"identity":"52d086ed-c273-453d-a6ae-d47884ae444e","added_by":"auto","created_at":"2020-04-02 20:33:21","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":216146,"visible":true,"origin":"","legend":"Correlation analysis. A. The change curve of body temperature and the change curve of daily CSF drainage volume; B. Correlation analysis of body temperature and daily CSF drainage volume; C. The change curve of WBC count and the change curve of daily CSF drainage volume; D. Correlation analysis of WBC count and daily CSF drainage volume; E. The change curve of polykaryocyte percentage and the change curve of daily CSF drainage volume; F. Correlation analysis of polykaryocyte percentage and daily CSF drainage volume; G. The change curve of WBC count and the change curve of polykaryocyte percentage; H. Correlation analysis of WBC count and polykaryocyte percentage. Data were represented as mean ± s.e.m.","description":"","filename":"3.png","url":"https://assets-eu.researchsquare.com/files/rs-19464/v1/3.png"},{"id":828114,"identity":"158062b7-0934-4da5-bea0-d15797c2d060","added_by":"auto","created_at":"2020-04-02 20:33:21","extension":"png","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":170006,"visible":true,"origin":"","legend":"A. The WBC count change curves of different daily CSF drainage volumes; B. Comparison of the retention time of LCD among the different daily CSF drainage volumes; C. WBC change curves of different antibiotics; D. Comparison of the retention time of LCD among the different antibiotics; E. Comparison of daily CSF drainage flows of different antibiotics. n.s.: no statistical significance; *: P\u003c0.05. Data were represented as mean ± s.e.m.","description":"","filename":"4.png","url":"https://assets-eu.researchsquare.com/files/rs-19464/v1/4.png"},{"id":828115,"identity":"1f925307-ed64-4d2a-b5f3-f4b5caf6f043","added_by":"auto","created_at":"2020-04-02 20:33:21","extension":"png","order_by":5,"title":"Figure 5","display":"","copyAsset":false,"role":"figure","size":182144,"visible":true,"origin":"","legend":"A. Comparison of the retention time and daily CSF drainage volume between supratentorial surgery and subtentorial surgery; B. Comparison of body temperature change curves between supratentorial surgery and subtentorial surgery; C. Comparison of WBC count change curves between supratentorial surgery and subtentorial surgery; D. Comparison of polykaryocyte percentage change curves between supratentorial surgery and subtentorial surgery. n.s.: no statistical significance; *: P\u003c0.05; **: P\u003c0.01; ***: P\u003c0.001. Data were represented as mean ± s.e.m.","description":"","filename":"5.png","url":"https://assets-eu.researchsquare.com/files/rs-19464/v1/5.png"},{"id":13496896,"identity":"baa5cb16-451b-4d85-a9b0-a5ad2034b869","added_by":"auto","created_at":"2021-09-16 22:51:29","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1541805,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-19464/v1/295352cc-d963-49de-8c3a-bf650d8e1ed9.pdf"}],"financialInterests":"","formattedTitle":"Dynamic curve analysis of indicators related to lumbar cistern drainage for postoperative meningitis","fulltext":[{"header":"Background","content":" \u003cp\u003eLumbar cistern drainage (LCD) is widely used in neurosurgery as an effective way to treat postoperative meningitis [\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e], vasospasm of subarachnoid hemorrhage [\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e, \u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e], ventricular system hemorrhage [\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e] and reduction of intracranial pressure in patients with severe craniocerebral trauma [\u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e]. Of note, meningitis after neurosurgical craniotomy is a common complication that affects the prognosis and length of stay of patients [\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e]. Although LCD can be used in a variety of clinical cases, there are risks and potential complications, such as infection, given that the process is invasive and requires placement of a drainage tube for a certain period. The white blood cell (WBC) count in cerebrospinal fluid (CSF) and the daily drainage volume of CSF should be observed clinically in order to guide decisions in catheter removal. However, with respect to LCD placement, there is a dearth of information available on how drainage time relates to the change trend of CSF-related indicators, and how these indicators correlate with one another during the interventional treatment process. Therefore, this study retrospectively analyzed 51 cases of LCD due to postoperative meningitis and plotted the dynamic change curves of body temperature, WBC count, polykaryocyte percentage, protein, glucose and chloride over a period of 13 days. The bivariate correlation between WBC count, polykaryocyte percentage, body temperature and daily CSF drainage volume was assessed. Lastly, to provide reference data for the application of LCD in clinical practice, the effect of daily drainage volumes, antibiotic choice and surgical sites on the WBC count change curve was investigated.\u003c/p\u003e "},{"header":"Materials And Methods","content":"\u003cp\u003e\u003cem\u003eCases and inclusion criteria\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eThe inclusion criteria of cases in this study were: 1) elective craniotomy; 2) elevated postoperative body temperature which remained above 37.5℃, with at least one of the following clinical symptoms: headache, neck stiffness, cranial nerve irritation symptoms, or disturbance of consciousness; 3) LCD was performed, and 4) in CSF during drainage, WBC count was greater than 500\u0026times;10\u003csup\u003e6\u003c/sup\u003e/L. In all, 51 patients in Shengjing Hospital of China Medical University met the above criteria between January 2012 and December 2019. Patient demographics included 23 males, 28 females, 23 cases of supratentorial surgery and 28 cases of subtentorial surgery (\u003cem\u003eTable 1\u003c/em\u003e). This study was approved by the ethics committee of the Shengjing Hospital of China Medical University. Informed consent was obtained from all patients.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eResearch process\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eFor all 51 cases, body temperature and routine CSF biochemical indicators, including WBC count, polykaryocyte percentage, protein, glucose and chloride, were recorded daily prior to catheter placement and for a period of 13 days after catheter placement. A bivariate correlation analysis was performed on the daily CSF drainage change curve, body temperature change curve, WBC change curve and polykaryocyte percentage change curve. Finally, according to the average daily drainage volume of each case, the differences in WBC change curves and drainage time between different drainage volumes were analyzed. According to the types of antibiotics used in the drainage process, the WBC change curve, drainage time and differences in the daily drainage volume between different antibiotics were analyzed. The differences in drainage time, daily drainage volume, body temperature curve, white blood cell change curve and polykaryocyte percentage change curve for various surgical sites were also analyzed (\u003cem\u003eFigure 1\u003c/em\u003e)\u003cem\u003e.\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eStatistical analysis\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eData were analyzed using SPSS17.0 software for statistical calculation. A \u003cem\u003et\u003c/em\u003e-test was used to determine the statistical differences between body temperature, WBC count, polykaryocyte percentage, protein, glucose and chloride at different time points. The same method was adopted to calculate statistical differences in drainage time and daily drainage volume between different groups. Lastly, the bivariate correlation between daily CSF drainage volume, body temperature, WBC and polykaryocyte percentage were analyzed. \u003cem\u003eP\u0026lt;0.05\u003c/em\u003e was considered statistically significant.\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003e\u003cem\u003eGeneral change trend of routine CSF biochemical tests\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eThe change trend of body temperature after LCD was as follows: body temperature first decreased, increased and then decreased. Body temperature on the second day after drainage was significantly different from body temperature before drainage (\u003cem\u003eP \u0026lt; 0.001\u003c/em\u003e). Body temperature began to increase on the sixth day after drainage and reached the highest point on the ninth day after drainage, after which it began to decrease (\u003cem\u003eFigure 2A\u003c/em\u003e). The WBC count on the first day after drainage was significantly higher than WBC count before drainage (\u003cem\u003eP\u0026lt;0.001\u003c/em\u003e), and then began to show an overall downward trend. By day 4, the WBC count was significantly lower than the WBC count before drainage (\u003cem\u003eP=0.004\u0026lt;0.01\u003c/em\u003e) (\u003cem\u003eFigure 2B\u003c/em\u003e). The change trend of the polykaryocyte percentage was similar to that of body temperature; it began to decrease significantly on the third day after drainage (\u003cem\u003eP=0.004\u0026lt;0.01\u003c/em\u003e) (\u003cem\u003eFigure 2C\u003c/em\u003e). The time node was synchronized with the change of WBC. Of note, protein was above the normal range during drainage (\u003cem\u003eFigure 2D\u003c/em\u003e), the change of glucose was within the normal range during drainage (\u003cem\u003eFigure 2E\u003c/em\u003e) and the change of chloride was essentially below the normal range during drainage (\u003cem\u003eFigure 2F\u003c/em\u003e). These trends were overall consistent with the characteristics of meningitis.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eCorrelation analysis of daily CSF drainage with body temperature and WBC\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eCorrelation analysis demonstrated a negative correlation between daily CSF drainage and body temperature (r = -0.14), and there was no statistical difference between the two trends (\u003cem\u003eP=0.65 \u0026gt; 0.05\u003c/em\u003e) (\u003cem\u003eFigure 3A, 3B\u003c/em\u003e). There was also a negative correlation between daily CSF drainage and WBC count (r = -0.56), with a statistical difference between the two trends (\u003cem\u003eP=0.046 \u0026lt; 0.05\u003c/em\u003e) (\u003cem\u003eFigure 3C, 3D\u003c/em\u003e). There was a negative correlation between daily CSF flow and polykaryocyte percentage (r = -0.29), with no statistical difference between the two trends (\u003cem\u003eP=0.34 \u0026gt; 0.05\u003c/em\u003e) (\u003cem\u003eFigure 3E, 3F\u003c/em\u003e). Lastly, there was a positive correlation between WBC count and polykaryocyte percentage (r = 0.696), and the change trend of the two was statistically different (\u003cem\u003eP=0.006 \u0026lt; 0.01\u003c/em\u003e) (\u003cem\u003eFigure 3G, 3H\u003c/em\u003e).\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eWhen the daily CSF drainage volume was 250-300 ml, the WBC change curve was most consistent with the overall WBC change curve \u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eBased on the observed average daily CSF drainage volumes, the patients were divided into five groups: 100-150 ml/d (n=11, 21.6%), 150-200 ml/d (n=19, 37.3%), 200-250 ml/d (n=9, 17.6%), 250-300 ml/d (n=8, 15.7%) and greater than 300 ml/d (n=4, 7.8%). The WBC change curves of the five groups all increased on the first day after drainage, and then presented an overall trend of decline. Among them, the WBC of the 250-300ml/d group decreased the most significantly on the fourth day after drainage (\u003cem\u003eP=0.006\u0026lt;0.01\u003c/em\u003e), and the subsequent fluctuation was smaller, which was most consistent with the overall WBC curve when compared with the other subgroups (\u003cem\u003eFigure 4A\u003c/em\u003e). In addition, there was no significant difference in drainage time between the five groups (\u003cem\u003eFigure 4B\u003c/em\u003e), indicating that although the WBC trend for the 200-250 ml/d group was most consistent with the overall WBC change curve, more daily flow did not shorten duration of LCD placement.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eThe type of antibiotic affects the WBC change curve\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003ePatients were divided into four groups according to the types of antibiotics used during drainage, as follows: cephalosporin treatment group (more than 3 generations of cephalosporin) (n=16, 31.4%), meropenem treatment group (n=10, 19.6%), linezolid treatment group (n=7, 13.7%) and multiple antibiotic treatment group (n=18, 35.3%). The WBC count change curve of the meropenem group and the multiple antibiotic group was consistent with the overall curve, while the cephalosporin group and linezolid group showed some fluctuations. The decrease of WBC on the fourth day of drainage was the most significant in the meropenem treatment group (\u003cem\u003eP=0.011\u0026lt;0.05\u003c/em\u003e) (\u003cem\u003eFigure 4C\u003c/em\u003e). In addition, the drainage time between the meropenem treatment group and the cephalosporin treatment group was relatively short, and there was a statistical difference in the drainage time between the cephalosporin treatment group and the linezolid treatment group (\u003cem\u003eP=0.012 \u0026lt; 0.05\u003c/em\u003e) and the multiple antibiotic treatment group (\u003cem\u003eP=0.021 \u0026lt; 0.05\u003c/em\u003e) (\u003cem\u003eFigure 4D\u003c/em\u003e). There was no significant statistical difference in the daily drainage volumes of the four groups (\u003cem\u003eP\u0026gt;0.05\u003c/em\u003e) (\u003cem\u003eFigure 4E\u003c/em\u003e).\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eDifferences in body temperature and WBC curve in different surgical sites\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eBased on the surgical site, patients were divided into two groups: the supratentorial craniotomy group (n=23, 45.1%) and the subtentorial craniotomy group (n=28, 54.9%). A statistical difference was observed in the drainage time between the two groups (\u003cem\u003eP=0.012\u0026lt;0.05\u003c/em\u003e), with a longer drainage time in the supratentorial craniotomy group, and no significant statistical difference was observed in the daily drainage volume between the two groups (\u003cem\u003eP\u0026gt;0.05\u003c/em\u003e) (\u003cem\u003eFigure 5A\u003c/em\u003e). The trends of body temperature, WBC and polykaryocyte percentage were similar in the two groups. However, according to the trend of body temperature changes of the two groups, the overall body temperature of the supratentorial surgery group was higher than that of the subtentorial surgery group. When comparing body temperature at each time point before and 5 days after drainage, there were statistically significant differences in body temperature between the two groups (\u003cem\u003eFigure 5B\u003c/em\u003e), suggesting that symptoms of postoperative meningitis may vary in different surgical sites and that symptoms of hyperthermia are more common in the supratentorial surgery group. Overall, the differences in WBC count (\u003cem\u003eFigure 5C\u003c/em\u003e) and polykaryocyte percentage (\u003cem\u003eFigure 5D\u003c/em\u003e) at each time point between the two groups were not particularly significant.\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003e\u003cem\u003eLCD retention time of 6 to 7 days may be ideal\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eIn this retrospective study of 51 patients undergoing LCD placement, we found an average drainage duration of 7 days, with the overall body temperature curve showing a trend of decrease, increase and then decrease, in which body temperature dropped to the nadir on the sixth day after drainage and reached an average of 37.3℃. In addition, the WBC count curve changed significantly from day four after drainage, when the average leucocyte count was 840\u0026times;10\u003csup\u003e6\u003c/sup\u003e/L, after which it decreased to 440\u0026times;10\u003csup\u003e6\u003c/sup\u003e/L on day six, considered the minimum WBC count required for enrollment. Similarly, the polykaryocyte percentage dropped to the nadir of 42.1%, followed by an upward trend for body temperature, WBC count and polykaryocyte percentage.\u003c/p\u003e\n\u003cp\u003eLCD is an effective treatment for postoperative meningitis. However, prolonged indwelling of drainage tubes \u003cem\u003ein vivo\u003c/em\u003e may increase the risk of drainage tube-related infections. One study [7] demonstrated that the infection rate associated with LCD is 31.28% between three and seven days of drainage, but when LCD exceeds seven days, the infection rate rises to 63.33%. In addition, another study [8] showed that between four and nine days is the peak period of infection associated with LCD. The WBC count change curve seen in our study showed a small increase after day seven and a more significant increase in the polykaryocyte percentage. It is suggested that the duration of drainage at any time is prolonged and the risk of infection associated with drainage tubes is increasing. Therefore, the rational management of CSF drainage tube affects the development of postoperative meningitis [9].\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eExploration of daily CSF drainage volume\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eThe daily CSF volume during LCD is a clinical index that needs to be measured and observed closely. The first study using an external lumbar drainage system was reported by Voursh in 1963 [10]. Although the technique of LCD is relatively safe and effective, it also has certain risks and fatal complications, such as headache with low cranial pressure and even cerebral hernia [11, 12]. The occurrence of cerebral hernia is related to the rate of drainage. The rate of CSF production in normal adults is 20 ml/h, indicating that about 480ml CSF is produced every day.\u003c/p\u003e\n\u003cp\u003eSetting the drainage volume in the lumbar cisterna drainage process is very important. However, as far as we know, there are no recommendations on the average daily CSF drainage volume. In our study, the average total drainage volume was 1428 ml, the average daily drainage volume was 207 ml and the average CSF replacement was about three times. Of the 51 patients, two patients presented with headache symptoms of low cranial pressure during LCD, and the average daily drainage volume of the two patients was 380 ml and 404ml, respectively. The risk of low cranial pressure was higher (50%) when the average drainage volume was above 300 ml/d. In addition, there was a negative correlation between the daily drainage volume and the WBC count. The average daily drainage volume on the first day was 149 ml, after which it increased to 221 ml/d and remained above the baseline of 200 ml/d thereafter. With the accumulation of drainage volume, the WBC count showed a decreasing trend. Of the four groups of daily drainage, the most significant change in the WBC was noted when the daily drainage volume of CSF was between 250 and 300 ml since the average WBC count was 2619\u0026times;10\u003csup\u003e6\u003c/sup\u003e/L before drainage and subsequently decreased to 655\u0026times;10\u003csup\u003e6\u003c/sup\u003e/L on day four of drainage. When the daily CSF drainage was maintained between 200 and 300ml, patients did not show symptoms of headache with low cranial pressure. This was consistent with the control of CSF drainage of 10 ml/h by Nanidis N et al. [13]. Therefore, in order to achieve the goal of reducing the WBC count of CSF more quickly, it is relatively safe and effective to maintain the average daily drainage volume at 250-300ml.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eSelection of antibiotics during LCD\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003ePostoperative meningitis after craniotomy is a common complication of neurosurgery and affects the prognosis of surgical patients. Some malignant tumors and tumors of the ventricular system are prone to cause postoperative intracranial infection [14,15]. Bacterial meningitis is more common in infection [16]. In our study, 51 patients were treated with at least one antibiotic during drainage. Among them, the WBC count change curve of the meropenem treatment group showed the most significant decrease in the WBC count at day four of drainage, and the drainage time of the LCD was shorter in the cephalosporin treatment group and the meropenem treatment group, suggesting that the infection rate of gram-negative bacilli may be higher in our cases. However, in all 51 cases, multiple CSF bacterial cultures were negative and the pathogen of infection could not be identified, which is also a limitation of this study. In our experience, the use of antibiotics during LCD can, on the one hand, treat meningitis and, on the other hand, reduce the risk of catheter-related infections.\u003c/p\u003e\n\u003cp\u003eIn addition, we found that there were notable differences in the clinical manifestations of postoperative meningitis among patients with different surgical sites. Patients who underwent supratentorial surgery tended to have a higher degree of fever, while patients who underwent subtentorial surgery had more symptoms of meningeal irritation, which required clinical screening.\u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003eThe study investigated parameters surrounding CSF change parameters when using LCD as an effective method to treat postoperative meningitis. We included 51 patients in this retrospective study and assessed the correlation and statistical significance of multiple parameters over a study duration of 13 days. The WBC count on day four after drainage showed a significant decrease compared with the WBC count before drainage. These results indicate that LCD retention time of six to seven days is ideal based on body temperature, WBC count and polykaryocyte percentage, and prolonged retention time may increase the risk associated with the drainage tube. Patients were treated with at least one antibiotic during the LCD process, and results suggest a possible prevalence of gram-negative bacilli given trends from antibiotic correlation studies.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eConsent for publication\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAll authors consent to the publication of this manuscript.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAcknowledgements\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCompeting interests\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare that they have no competing interests.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthor contributions\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAll authors were involved in the study design, interpretation of the results, and the reviewing and approval of the manuscript, and in the decision to submit the article for publication. All authors also confirm accountability for the accuracy and integrity of the work.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthics approval and consent to participate\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eInformed consent from each patient was carried out before the research. The use of the research protocol was approved by the Ethics and the Human Research Review Committee of Shengjing Hospital of China Medical University.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAvailability of data and materials\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTo get the raw data, please send an email to authors. 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The\u0026nbsp;incidence\u0026nbsp;and\u0026nbsp;risk factors\u0026nbsp;of\u0026nbsp;meningitis\u0026nbsp;after\u0026nbsp;major\u0026nbsp;craniotomy\u0026nbsp;in\u0026nbsp;China: a\u0026nbsp;retrospectivecohort study. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/25003204\"\u003e\u003cem\u003ePLoS One\u003c/em\u003e.\u003c/a\u003e2014; 9(7): e101961.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Scheithauer%20S%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eScheithauer S\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=B%C3%BCrgel%20U%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eB\u0026uuml;rgel U\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Bickenbach%20J%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eBickenbach J\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=H%C3%A4fner%20H%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eH\u0026auml;fner H\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Haase%20G%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eHaase G\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Waitschies%20B%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eWaitschies B\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Reinges%20MH%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eReinges MH\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Lemmen%20SW%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=20333433\"\u003eLemmen SW\u003c/a\u003e. External\u0026nbsp;ventricular\u0026nbsp;and lumbar drainage-associated meningoventriculitis: prospective analysis of time-dependent infection rates and risk factor analysis. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/20333433\"\u003e\u003cem\u003eInfection\u003c/em\u003e.\u003c/a\u003e2010; 38(3): 205-209.\u0026nbsp;\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Soavi%20L%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eSoavi L\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Rosina%20M%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eRosina M\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Stefini%20R%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eStefini R\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Fratianni%20A%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eFratianni A\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Cadeo%20B%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eCadeo B\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Magri%20S%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eMagri S\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Latronico%20N%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eLatronico N\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Fontanella%20M%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eFontanella M\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Signorini%20L%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=28031985\"\u003eSignorini L\u003c/a\u003e. Post-neurosurgical\u0026nbsp;meningitis:\u0026nbsp;Management\u0026nbsp;of\u0026nbsp;cerebrospinal\u0026nbsp;fluid\u0026nbsp;drainage\u0026nbsp;catheters\u0026nbsp;influencesthe\u0026nbsp;evolution\u0026nbsp;of\u0026nbsp;infection. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=neurosurgical+meningitis:+Management+of+cerebrospinal+fluid+drainage+catheters+influences+the+evolution+of+infection\"\u003e\u003cem\u003eSurg Neurol Int\u003c/em\u003e.\u003c/a\u003e2016; 7(Suppl 39): S927-S934.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Wahlig%20JB%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=9932901\"\u003eWahlig JB\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Welch%20WC%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=9932901\"\u003eWelch WC\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Kang%20JD%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=9932901\"\u003eKang JD\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Jungreis%20CA%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=9932901\"\u003eJungreis CA\u003c/a\u003e. Cervical\u0026nbsp;intrathecal\u0026nbsp;catheter\u0026nbsp;placement\u0026nbsp;for\u0026nbsp;cerebrospinal\u0026nbsp;fluid drainage: technical case report. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/9932901\"\u003e\u003cem\u003eNeurosurgery\u003c/em\u003e.\u003c/a\u003e1999; 44(2): 419-421.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Manley%20GT%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=10701537\"\u003eManley GT\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Dillon%20W%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=10701537\"\u003eDillon W\u003c/a\u003e. Acute\u0026nbsp;posterior\u0026nbsp;fossa\u0026nbsp;syndrome\u0026nbsp;following\u0026nbsp;lumbar\u0026nbsp;drainage\u0026nbsp;for\u0026nbsp;treatment\u0026nbsp;of\u0026nbsp;suboccipitalpseudomeningocele. Report of three cases. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Acute+posterior+fossa+syndrome+following+lumbar+drainage+for+treatment+of+suboccipital+pseu-domeningocele\"\u003e\u003cem\u003eJ Neurosurg\u003c/em\u003e.\u003c/a\u003e2000; 92(3): 469-474.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=A%C3%A7ikba%C5%9F%20SC%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=12111503\"\u003eA\u0026ccedil;ikbaş SC\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Aky%C3%BCz%20M%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=12111503\"\u003eAky\u0026uuml;z M\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Kazan%20S%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=12111503\"\u003eKazan S\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Tuncer%20R%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=12111503\"\u003eTuncer R\u003c/a\u003e. Complications\u0026nbsp;of\u0026nbsp;closed\u0026nbsp;continuous\u0026nbsp;lumbar\u0026nbsp;drainage\u0026nbsp;of\u0026nbsp;cerebrospinal fluid. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/12111503\"\u003e\u003cem\u003eActa Neurochir (Wien)\u003c/em\u003e.\u003c/a\u003e2002; 144(5): 475-480.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Nanidis%20N%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=25179872\"\u003eNanidis N\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Korfias%20S%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=25179872\"\u003eKorfias S\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Sakas%20DE%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=25179872\"\u003eSakas DE\u003c/a\u003e. Flow-regulated\u0026nbsp;external\u0026nbsp;lumbar\u0026nbsp;drain: applications and complications. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Nanidis+N+Flow-regulated+external+lumbar+drain\"\u003e\u003cem\u003eActa Neurochir (Wien)\u003c/em\u003e.\u003c/a\u003e2014; 156(11): 2201-2205.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Zhou%20H%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=25395855\"\u003eZhou H\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Zhang%20X%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=25395855\"\u003eZhang X\u003c/a\u003e. Intracranial\u0026nbsp;malignant\u0026nbsp;lesions\u0026nbsp;correlate\u0026nbsp;with the\u0026nbsp;requirement\u0026nbsp;for a\u0026nbsp;long\u0026nbsp;treatment\u0026nbsp;course\u0026nbsp;in\u0026nbsp;postoperative\u0026nbsp;central\u0026nbsp;nervous\u0026nbsp;system\u0026nbsp;infection. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=intracranial+malignant+lesions+correlate+with+the+requirement+for+a+long+treatment+course+in+postoperative+central+nervous+system+infection\"\u003e\u003cem\u003eNeuropsychiatr Dis Treat\u003c/em\u003e.\u003c/a\u003e2014; 10: 2071-2077.\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Huang%20B%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=31276518\"\u003eHuang B\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Ren%20Y%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=31276518\"\u003eRen Y\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Wang%20C%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=31276518\"\u003eWang C\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Lan%20Z%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=31276518\"\u003eLan Z\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Hui%20X%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=31276518\"\u003eHui X\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Liu%20W%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=31276518\"\u003eLiu W\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Zhang%20Y%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=31276518\"\u003eZhang Y\u003c/a\u003e. Risk factors\u0026nbsp;for\u0026nbsp;postoperative\u0026nbsp;meningitis\u0026nbsp;after\u0026nbsp;microsurgery\u0026nbsp;for\u0026nbsp;vestibular schwannoma. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/31276518\"\u003e\u003cem\u003ePLoS One\u003c/em\u003e.\u003c/a\u003e2019; 14(7): e0217253.\u0026nbsp;\u003c/li\u003e\n\u003cli\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Chen%20S%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=29288858\"\u003eChen S\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Cui%20A%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=29288858\"\u003eCui A\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Yu%20K%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=29288858\"\u003eYu K\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Huang%20C%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=29288858\"\u003eHuang C\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Zhu%20M%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=29288858\"\u003eZhu M\u003c/a\u003e,\u0026nbsp;\u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Chen%20M%5bAuthor%5d\u0026amp;cauthor=true\u0026amp;cauthor_uid=29288858\"\u003eChen M\u003c/a\u003e. Risk\u0026nbsp;Factors\u0026nbsp;Associated\u0026nbsp;with\u0026nbsp;Meningitis\u0026nbsp;after\u0026nbsp;Neurosurgery: A\u0026nbsp;Retrospective\u0026nbsp;Cohort\u0026nbsp;Study\u0026nbsp;in a\u0026nbsp;Chinese\u0026nbsp;Hospital. \u003ca href=\"https://www.ncbi.nlm.nih.gov/pubmed/?term=Risk+Factors+Associated+with+Meningitis+after+Neurosurgery:+A+Retrospective+Cohort+Study+in+a+Chinese+Hospital\"\u003e\u003cem\u003eWorld Neurosurg\u003c/em\u003e.\u003c/a\u003e2018; 111: e546-e563.\u003c/li\u003e\n\u003c/ol\u003e"},{"header":"Tables","content":"\u003cp style=\"margin: 0in 0in 0.0001pt;font-size:14px;font-family: Calibri, sans-serif;text-align: left;\"\u003e\u003cspan style=\"font-family: Verdana, Geneva, sans-serif; font-size: 10px; color: rgb(0, 0, 0);\"\u003eTable 1. The demographic of the cases\u003c/span\u003e\u003c/p\u003e\n\u003cdiv align=\"center\"\u003e\n \u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border-collapse: collapse;border: none;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eCase number\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eSex\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eAge\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e(Years)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eSurgical site\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eDuration for lumbar drainage\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e(Days)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTotal drainage volume\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e(mL)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;border-top-width: 1pt;border-style: solid none;border-top-color: windowtext;border-bottom-width: 1pt;border-bottom-color: windowtext;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eAverage daily drainage volume\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e(mL)\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;border: none;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;border: none;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;border: none;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e34\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;border: none;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight frontotemporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;border: none;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e10\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;border: none;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1320\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;border: none;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e132\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e48\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight lateral ventricle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e10\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2055\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e206\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e3\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e70\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e11\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2640\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e240\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e4\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e37\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft frontal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e13\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2510\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e193\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e5\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e63\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTrigeminal nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e6\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e890\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e148\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e6\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e29\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1060\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1514\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e43\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e8\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1090\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e136\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e8\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e53\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eCerebellum\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e8\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e980\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e122\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e9\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e45\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e4\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e630\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e158\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e10\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e61\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTrigeminal nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e5\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1380\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e276\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e11\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e53\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFacial 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10px;\"\u003e1130\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e188\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 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10px;\"\u003e135\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e13\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 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10px;\"\u003e59\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e832\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e119\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e15\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e69\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight frontal 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10px;\"\u003e1795\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e256\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e16\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e51\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e5\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1420\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e284\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e17\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 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10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e60\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft temporal 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10px;\"\u003e61\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTrigeminal nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 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10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e61\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e4\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e730\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e183\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e24\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e59\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eBrain stem\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2040\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e291\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e25\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e54\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e9\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1350\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e150\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e26\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e43\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e6\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1530\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e255\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e27\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e23\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1130\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e161\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e28\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e47\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMultiple supratentorial lesions\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e11\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2750\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e250\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e29\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e47\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e5\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e910\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e182\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e30\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e55\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFacial nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e5\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1600\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e320\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e31\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e39\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft frontal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2020\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e289\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e32\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e64\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight middle cranial fossa base\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e5\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1160\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e232\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e33\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e41\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight frontal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e12\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e3565\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e297\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e34\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e60\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e920\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e131\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e35\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e51\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e8\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1190\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e149\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e36\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e44\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e9\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1880\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e209\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e37\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e46\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1380\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e197\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e38\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e18\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e8\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1590\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e199\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e39\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e52\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTrigeminal nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e6\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e865\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e144\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e40\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e41\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft frontotemporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e10\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e2020\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e202\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e41\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e27\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight occipital lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1560\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e223\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e42\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e27\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eSaddle area\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e9\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1755\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e195\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e43\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e63\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTrigeminal nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e4\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e635\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e159\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e44\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e65\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTrigeminal nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e5\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e920\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e184\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e45\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e43\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight cerebellopontine angle\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e8\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1720\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e215\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e46\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e51\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eRight temporal lobe\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e872\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e125\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e47\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e29\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eLeft temporal 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10px;\"\u003e1570\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e196\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e48\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eMale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e39\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFacial nerve\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e7\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 1.4in;padding: 0in 5.4pt;\" width=\"18.0349932705249%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e1222\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e175\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e49\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43.8pt;padding: 0in 5.4pt;\" width=\"7.806191117092867%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eFemale\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42pt;padding: 0in 5.4pt;\" width=\"7.537012113055182%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e59\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eTrigeminal 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10px;\"\u003e2150\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 101.65pt;padding: 0in 5.4pt;\" width=\"18.304172274562585%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003e358\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 71.75pt;padding: 0in 5.4pt;\" width=\"12.920592193808883%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 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10px;\"\u003e50\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 109.2pt;padding: 0in 5.4pt;\" width=\"19.65006729475101%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 10px;\"\u003eCerebellum\u003c/span\u003e\u003c/span\u003e\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87.6pt;padding: 0in 5.4pt;\" width=\"15.746971736204577%\"\u003e\n \u003cp style=\"margin: 0in 0in 0.0001pt;text-align: center;font-size:14px;font-family: Calibri, sans-serif;vertical-align: middle;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e\u003cspan style=\"font-family: \n Verdana, Geneva, sans-serif;\"\u003e\u003cspan style=\"font-size: \n 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0);\"\u003e380\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003c/table\u003e\n\u003c/div\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Lumbar cisterna drainage, White blood cell, Polykaryocyte, Drainage volume","lastPublishedDoi":"10.21203/rs.3.rs-19464/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-19464/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"Background\n\nLumbar cisterna drainage (LCD) is widely used in neurosurgery as an effective treatment for postoperative meningitis, vasospasm of subarachnoid hemorrhage and ventricular system hemorrhage, and for reducing intracranial pressure in patients with severe craniocerebral trauma. The purpose of this work was two-fold: to analyze the dynamic curve of cerebrospinal fluid (CSF) related indices in cases of postoperative meningitis after selective craniotomy and to provide reference data for the clinical treatment with LCD.\n\nMethods\n\nWe conducted a retrospective study of LCD placement in patients who underwent either supratentorial craniotomy (n=23) or subtentorial craniotomy (m=28). Primary outcomes measured included pre-intervention and post-intervention dynamic changes of body temperature, and CSF biochemical parameters (white blood cell (WBC) count, polykaryocyte percentage, protein, glucose and chloride) over the course of 13 days of catheter placement. We also assessed the bivariate correlation between WBC count changes, polykaryocyte percentage, body temperature and daily CSF drainage volume. Finally, we analyzed the effect of average daily drainage volume, antibiotic choice, and surgical site on the WBC count change curves.\n\nResults\n\nAfter LCD, a trend of increased WBC count was observed on the first day of drainage, followed by an overall decrease in WBC count. There was a statistically significant ( P\u003c0.05 ) difference between the WBC count before drainage and the WBC count on the fourth day of drainage. Polykaryocyte percentage decreased initially and then increased progressively each day after drainage. There was a negative correlation between the change curve of the WBC count and the curve of daily drainage volume (r = -0.56). When the daily drainage volume was 250-300 ml/d, the change curve pattern of the WBC count was consistent with the overall trend of the WBC count, and there was no significant difference in the curve of the WBC count between different surgical sites ( P \u003e 0.05 ).\n\nConclusions\n\nLCD is an effective method for the treatment of postoperative meningitis. The WBC count can decrease significantly by the fourth day after drainage, and placement of the LCD for six to seven days is ideal. An average drainage volume of 250-300 ml/d is safe and effective.","manuscriptTitle":"Dynamic curve analysis of indicators related to lumbar cistern drainage for postoperative meningitis","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2020-04-02 20:33:18","doi":"10.21203/rs.3.rs-19464/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"2dd8ff79-0d83-4bbd-a75e-c52d91a8906a","owner":[],"postedDate":"April 2nd, 2020","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":78439,"name":"General Microbiology"},{"id":78440,"name":"Infectious Diseases"}],"tags":[],"updatedAt":"2021-07-27T20:47:45+00:00","versionOfRecord":{"articleIdentity":"rs-19464","link":"https://doi.org/10.1016/j.wneu.2021.04.031","journal":{"identity":"world-neurosurgery","isVorOnly":true,"title":"World Neurosurgery"},"publishedOn":"2021-07-01 20:47:45","publishedOnDateReadable":"July 1st, 2021"},"versionCreatedAt":"2020-04-02 20:33:18","video":"","vorDoi":"10.1016/j.wneu.2021.04.031","vorDoiUrl":"https://doi.org/10.1016/j.wneu.2021.04.031","workflowStages":[]},"version":"v1","identity":"rs-19464","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-19464","identity":"rs-19464","version":["v1"]},"buildId":"_2-kVJe1T_tPrBINL-cwx","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}

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