Use of botulinum toxin type A associated with nonthermal microneedling for treating erythematoustelangiectatic rosacea: case report

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Abstract

Treatments for rosacea control the pathology for a short period of time, requiring daily maintenance with topical and oral cosmetics. This research aimed to report the result of treatment with microneedling associated with botulinum toxin type A in a 37-years old female affected by erythematoustelangiectatic rosacea. The procedure consisted in applying botulinum toxin type A (100 UI diluted in 4 ml of saline, via drug delivery), with the electric nonthermal microneedling device. It was performed in 2 sessions, with an interval of 15 days. The evaluation was done 45 days after the first session through the Evaluation Form facial, photographs, quality of life questionnaire – RosaQol, and evaluation by CEA (Clinician Erythema Assessment). As a result, improvements were observed in skin texture, in the flushing and in the participant's quality of life. It was concluded that the technique improved the appearance of rosacea flushing, as well as a decrease in telangiectasias. Still, more studies and practical research are needed to determine the number of sessions and on the adjusted amount of A botulinum toxin used in the therapeutic correlated to the rosacea severity.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00